Assess pain (intensity, location) periodically throughout therapy. Patient may experience a transient increase in bone pain for 23 days, beginning 23 days after administration. This is normal, and increasing analgesic doses may be required. Pain should begin to diminish after 12 wk or longer and may allow for reduction or discontinuation of analgesics. Effects may continue for several months.Lab Test Considerations
Monitor hematologic parameters (WBC, platelets) at least once every other week during therapy. Platelets are usually ↓ 30% from preadministration levels. The nadir of thrombocytopenia is 1216 wk. Leukopenia may also occur. Recovery to preadministration levels usually occurs within 6 mo.
strontium-89 chloride has been found in Davis's Drug Guide
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