Recovery period after MI;
Concurrent electroconvulsive therapy;
Concurrent MAO inhibitor therapy (may result in serious, potentially fatal reactions).Use Cautiously in:
May ↑ risk of suicide attempt/ideation especially during early treatment or dose adjustment;
Severe hepatic or renal disease (dose ↓ recommended);
Lactation: Discontinue drug or bottle feed;
Pedi: Suicide risk may be greater in children and adolescents; safe use not established;
Geri: Initial dose ↓ recommended; use extended-release tablets with caution.