• (TMP = trimethoprim; SMX = sulfamethoxazole).Dosing based on TMP content.

• PO, IV (Adults and Children >2 mo): Mild-moderate infections—6–12 mg TMP/kg/day divided q 12 hr; Serious infection/Pneumocystis—15–20 mg TMP/kg /day/divided q 6–8 hr..

• PO (Adults): Urinary tract infection/chronic bronchitis—1 double strength tablet (160 mg TMP/800 mg SMX) q 12 hr for 10–14 days..

• PO, IV (Adults and Children >2 mo): 2 mg TMP/kg/dose daily or 5 mg TMP/kg/dose twice weekly..

• PO (Adults): 1 double strength tablet (160 mg TMP/800 mg SMX) daily (may also be given 3 times weekly)..

• PO (Children >1 mo): 150 mg TMP/m²/day divided q 12 hr or given as a single dose on 3 consecutive days/wk (not to exceed 320 mg TMP/1600 mg SMX per day)..