(TMP = trimethoprim; SMX = sulfamethoxazole).Dosing based on TMP content.Bacterial Infections
PO, IV (Adults and Children >2 mo): Mild-moderate infections612 mg TMP/kg/day divided q 12 hr; Serious infection/Pneumocystis1520 mg TMP/kg /day/divided q 68 hr..
PO (Adults): Urinary tract infection/chronic bronchitis1 double strength tablet (160 mg TMP/800 mg SMX) q 12 hr for 1014 days.. Urinary Tract Infection Prophylaxis
PO, IV (Adults and Children >2 mo): 2 mg TMP/kg/dose daily or 5 mg TMP/kg/dose twice weekly..P. jirovecii Pneumonia (Prevention)
PO (Adults): 1 double strength tablet (160 mg TMP/800 mg SMX) daily (may also be given 3 times weekly)..
PO (Children >1 mo): 150 mg TMP/m2/day divided q 12 hr or given as a single dose on 3 consecutive days/wk (not to exceed 320 mg TMP/1600 mg SMX per day)..
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