Davis's Lab & Diagnostic Tests
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Renin

General

Synonym/Acronym:
Plasma renin activity (PRA).

Common Use:
To assist in evaluating for a possible cause of hypertension.

Specimen:
Plasma (3 mL) collected in a lavender-top (EDTA) tube.

Normal Findings:
(Method: Radioimmunoassay)

Age and PositionConventional UnitsSI Units (Conventional Units × 1)
Newborn–12 mo2–35 ng/mL/hr2–35 ng/mL/hr
Supine, normal sodium diet
 1–3 yr1.7–11.2 ng/mL/hr1.7–11.2 mcg/L/hr
 4–5 yr1.0–6.5 ng/mL/hr1.0–6.5 mcg/L/hr
 6–10 yr0.5–5.9 ng/mL/hr0.5–5.9 mcg/L/hr
 11–15 yr0.5–3.3 ng/mL/hr0.5–3.3 mcg/L/hr
 Adult0.2–2.3 ng/mL/hr0.2–2.3 mcg/L/hr
Upright, normal sodium diet
 Adult–older adult1.3–4 ng/mL/hr1.3–4 mcg/L/hr
Values vary according to the laboratory performing the test, as well as the patient’s age, gender, dietary pattern, state of hydration, posture, and physical activity.

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