General
Synonym/Acronym:
Serum glutamic-oxaloacetic transaminase, AST, SGOT.
Common Use:
Considered an indicator of cellular damage in liver disease, such as hepatitis or cirrhosis; and in heart disease, such as myocardial infarction.
Specimen:
Serum (1 mL) collected in a red- or tiger-top tube.
Normal Findings:
(Method: Spectrophotometry, enzymatic at 37°C)
| Age | Conventional Units | SI Units (Conventional Units × 0.017) |
|---|
| Newborn | 25–75 units/L | 0.43–1.28 micro kat/L |
| 10 days–23 mo | 15–60 units/L | 0.26–1.02 micro kat/L |
| 2–3 yr | 10–56 units/L | 0.17–0.95 micro kat/L |
| 4–6 yr | 20–39 units/L | 0.34–0.66 micro kat/L |
| 7–19 yr | 12–32 units/L | 0.20–0.54 micro kat/L |
| 20–49 yr | | |
| Male | 20–40 units/L | 0.34–0.68 micro kat/L |
| Female | 15–30 units/L | 0.26–0.51 micro kat/L |
| Greater than 50 yr (older adult) | | |
| Male | 10–35 units/L | 0.17–0.60 micro kat/L |
| Greater than 45 yr (older adult) | | |
| Female | 10–35 units/L | 0.17–0.60 micro kat/L |
| Values may be slightly elevated in older adults due to the effects of medications and the presence of multiple chronic or acute diseases with or without muted symptoms. |
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