Davis's Lab & Diagnostic Tests

Calcium, Ionized

General

Synonym/Acronym:
Free calcium, unbound calcium, Ca++, Ca2+.

Common Use:
To investigate various conditions related to altered levels of ionized calcium such as hypocalcemia and hypercalcemia.

Specimen:
Serum (1 mL) collected in a red- or tiger-top tube. Specimen should be transported tightly capped and remain unopened until testing. Exposure of serum to room air changes the pH of the specimen due to the release of carbon dioxide and can cause erroneous results.

Normal Findings:
(Method: Ion-selective electrode)

AgeConventional UnitsSI Units (Conventional Units × 0.25)
Whole blood
 0–11 mo4.2–5.84 mg/dL1.05–1.46 mmol/L
1 yr-Adult4.6–5.08 mg/dL1.12–1.32 mmol/L
Plasma
Adult4.12–4.92 mg/dL1.03–1.23 mmol/L
Serum
1–18 yr4.8–5.52 mg/dL1.2–1.38 mmol/L
Adult4.64–5.28 mg/dL1.16–1.32 mmol/L

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