Nursing Central: Protein, Blood, Total and Fractions

Protein, Blood, Total and Fractions

General

Synonym/Acronym:
TP, SPEP (fractions include albumin, α₁-globulin, α₂-globulin, β-globulin, and γ-globulin).

Common Use:
To assess nutritional status related to various disease and conditions such as dehydration, burns, and malabsorption.

Specimen:
Serum (1 mL) collected in a red- or tiger-top tube.

Normal Findings:
(Method: Spectrophotometry for total protein, electrophoresis for protein fractions)

Total Protein

Age	Conventional Units	SI Units (Conventional units × 10)
Newborn–5 days	3.8–6.2 g/dL	38–62 g/L
1–3 yr	5.9–7 g/dL	59–70 g/L
4–6 yr	5.9–7.8 g/dL	59–78 g/L
7–9 yr	6.2–8.1 g/dL	62–81 g/L
10–19 yr	6.3–8.6 g/dL	63–86 g/L
Adult	6–8 g/dL	60–80 g/L
Values may be slightly decreased in older adults due to insufficient intake or the effects of medications and the presence of multiple chronic or acute diseases with or without muted symptoms.

Protein Fractions

	Conventional Units	SI Units (Conventional Units × 10)
Albumin	3.4–4.8 g/dL	34–48 g/L
α₁-Globulin	0.2–0.4 g/dL	2–4 g/L
α₂-Globulin	0.4–0.8 g/dL	4–8 g/L
β-Globulin	0.5–1 g/dL	5–10 g/L
γ-Globulin	0.6–1.2 g/dL	6–12 g/L
Values may be slightly decreased in older adults due to insufficient intake or the effects of medications and the presence of multiple chronic or acute diseases with or without muted symptoms.

Protein, Blood, Total and Fractions has been found in Davis's Lab & Diagnostic Tests

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