Nursing Central: CD4/CD8 Enumeration

CD4/CD8 Enumeration

General

Synonym/Acronym:
T-cell profile.

Common Use:
To monitor HIV disease progression and the effectiveness of retroviral therapy.

Specimen:
Whole blood (1 mL) collected in a green-top (heparin) tube.

Normal Findings:
(Method: Flow cytometry)

	Mature T cells (CD3)		Helper T cells (CD4)		Suppressor T cells (CD8)
Age	Absolute (cells/mm³)	%	Absolute (cells/mm³)	%	Absolute (cells/mm³)	%
0–2 mo	2,500–5,500	53–84	1,600–4,000	35–64	560–1,700	12–28
3–5 mo	2,500–5,600	51–77	1,800–4,000	35–56	590–1,600	12–23
6–11 mo	1,900–5,900	49–76	1,400–4,300	31–56	500–1,700	12–24
12–23 mo	2,100–6,200	53–75	1,300–3,400	32–51	620–2,000	14–30
2–5 yr	1,400–3,700	56–75	700–2,200	28–47	490–1,300	16–30
6–11 yr	1,200–2,600	60–76	650–1,500	31–47	370–1100	18–35
12–17 yr	1,000–2,200	56–84	530–1,300	31–52	330–920	18–35
Adult	527–2,846	49–81	332–1,642	28–51	170–811	12–38

CD4/CD8 Enumeration has been found in Davis's Lab & Diagnostic Tests

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