Nursing Central: Catecholamines, Blood and Urine

Catecholamines, Blood and Urine

General

Synonym/Acronym:
Epinephrine, norepinephrine, dopamine.

Common Use:
To assist in diagnosing catecholamine-secreting tumors, such as those found in the adrenal medulla, and in the investigation of hypertension. The urine test is used to assist in diagnosing pheochromocytoma and as a work-up of neuroblastoma.

Specimen:
Plasma (2 mL) collected in green-top (heparin) tube. Urine (25 mL) from a timed specimen collected in a clean, plastic, amber collection container with 6N hydrochloric acid as a preservative.

Normal Findings:
(Method: High-performance liquid chromatography)

Blood	Conventional Units	SI Units
(Conventional Units × 5.46)
Epinephrine
Newborn–1 yr	0–34 pg/mL	0–186 pmol/L
1–18 yr	0–80 pg/mL	0–437 pmol/L
Adult
Supine, 30 min	0–110 pg/mL	0–600 pmol/L
Standing, 30 min	0–140 pg/mL	0–764 pmol/L
(Conventional Units × 5.91)
Norepinephrine
Newborn–1 yr	0–659 pg/mL	0–3,895 pmol/L
1–18 yr	0–611 pg/mL	0–3,611 pmol/L
Adult
Supine, 30 min	70–750 pg/mL	414–4,432 pmol/L
Standing, 30 min	200–1,700 pg/mL	1,182–10,047 pmol/L
(Conventional Units × 6.53)
Dopamine
Newborn–1 yr	0–42 pg/mL	0–274 pmol/L
1–18 yr	0–32 pg/mL	0–209 pmol/L
Adult
Supine or standing	0–48 pg/mL	0–313 pmol/L

Urine	Conventional Units	SI Units
(Conventional Units × 5.46)
Epinephrine
Newborn–9 yr	0–11.0 mcg/24 hr	0–60.1 nmol/24 hr
10–19 yr	0–18.0 mcg/24 hr	0–98.3 nmol/24 hr
20 yr–older adult	0–20 mcg/24 hr	0–109 nmol/24 hr
(Conventional Units × 5.91)
Norepinephrine
Newborn–9 yr	0–59 mcg/24 hr	0–349 nmol/24 hr
10–19 yr	0–90 mcg/24 hr	0–532 nmol/24 hr
20 yr–older adult	0–135 mcg/24 hr	0–798 nmol/24 hr
(Conventional Units × 6.53)
Dopamine
Newborn–9 yr	0–414 mcg/24 hr	0–2,703 nmol/24 hr
10–19 yr	0–575 mcg/24 hr	0–3,755 nmol/24 hr
20 yr–older adult	0–510 mcg/24 hr	0–3,330 nmol/24 hr

Catecholamines, Blood and Urine has been found in Davis's Lab & Diagnostic Tests

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