Increased susceptibility to rheumatic fever is known to occur in families. The human leukocyte antigen type DR7DR53 has been associated with the development of valve lesions in severe RHD patients. A novel B-cell alloantigen marker, 883, was identified as a marker, and while genetic studies have observed an autosomal recessive pattern of inheritance, causative mutations remain to be found.
Rheumatic Fever, Acute has been found in Diseases and Disorders
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