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Table 3.16. Diagnostic Tests for Hepatitis B Virus (HBV) Antigens and Antibodies

Table 3-16

Factors To Be TestedHBV Antigen or AntibodyUse
HBsAgHepatitis B surface antigenDetection of acutely or chronically infected people; antigen used in hepatitis B vaccine
Anti-HBsAntibody to HBsAgIdentification of people who have resolved infections with HBV; determination of immunity after immunization
HBeAgHepatitis B e antigenIdentification of infected people at increased risk of transmitting HBV
Anti-HBeAntibody to HBeAgIdentification of infected people with lower risk of transmitting HBV
Anti-HBcAntibody to HBcAgaIdentification of people with acute, resolved, or chronic HBV infection (not present after immunization)
IgM anti-HBcIgM antibody to HBcAgIdentification of people with acute or recent HBV infections (including HBsAg-negative people during the "window" phase of infection)


HBcAg indicates hepatitis B core antigen; IgM, immunoglobulin M.

Footnotes

a. No test is available commercially to measure HBcAg.

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