Most human infections are asymptomatic. Acute symptomatic infection is characterized by rapid onset of nausea, vomiting, abdominal discomfort or pain, and bloody or watery mucoid diarrhea. In many patients, the course is chronic with intermittent episodes of diarrhea, anorexia, and weight loss. Rarely, organisms spread to mesenteric nodes, pleura, or liver. Inflammation of the gastrointestinal tract and local lymphatic vessels can result in bowel dilation, ulceration, and secondary bacterial invasion. Colitis produced by Balantidium coli often is indistinguishable from that produced by Entamoeba histolytica . Fulminant disease can occur in malnourished or otherwise debilitated or immunocompromised patients.
Balantidium coli Infections has been found in Red Book 28e
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