Red Book: Table 4.6. Drugs for Invasive and Other Serious Fungal Infections

Table 4.6. Drugs for Invasive and Other Serious Fungal Infections

Table 4-6

	Intravenous		Oral	Intravenous or Oral
Disease	Amphotericin B	Caspofungin,^a Micafungin,^a,^b or Anidulafungin,^a,^b	Flucytosine	Itraconazole^a	Fluconazole^a	Voriconazole^a
Aspergillosis	A	A	…	M	…	P
Blastomycosis	P	…	…	M	M	…
Candidiasis:
Chronic, mucocutaneous	A	A	…	A	P	A
Oropharyngeal, esophageal	P(severe cases)	P	…	A	P	A
Systemic	P^d	P	S	…	P, M	A
Coccidioidomycosis	P	…	…	P, M	P, M	…
Cryptococcosis	P, S	…	S	…	A, M	…
Fusariosis	P	…	…	…	…	P
Histoplasmosis	P	…	…	P, A	A, M	…
Mucormycosis (zygomycosis)	P	…	…	…	…	…
Paracoccidioidomycosis	P^c	…	…	P, M	…	…
Pseudallescheriasis	…	…	…	M	…	P
Sporotrichosis	P	…	…	M	…	…

P indicates preferred treatment in most cases; A, efficacy less well established or alternative drug; M, for mild and moderately severe cases; S, combination recommended if infection is severe or central nervous system is involved.

Table 4.6. Drugs for Invasive and Other Serious Fungal Infections has been found in Red Book 28e

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Table 4.6. Drugs for Invasive and Other Serious Fungal Infections

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Table 4-6

Last updated: July 12, 2012

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