Table 3-51
| Susceptibility Test Results | Antimicrobial Managementa |
| •Susceptible to penicillin | Discontinue vancomycin |
| AND |
| Begin penicillin (and discontinue cephalosporin) |
| OR |
| Continue cefotaxime or ceftriaxone aloneb |
| •Nonsusceptible to penicillin (intermediate or resistant) | Discontinue vancomycin |
| AND |
| AND | Continue cefotaxime or ceftriaxone |
| Susceptible to cefotaxime and ceftriaxone | |
| •Nonsusceptible to penicillin (intermediate or resistant) | Continue vancomycin and high-dose cefotaxime or ceftriaxone |
| AND | AND |
| Nonsusceptible to cefotaxime and ceftriaxone (intermediate or resistant) | Rifampin may be added in selected circumstances (see text) |
| AND | |
| Susceptible to rifampin | |
Table 3.51. Antimicrobial Therapy for Infants and Children With Meningitis Caused by Streptococcus Pneumoniae on the Basis of Susceptibility Test Results has been found in Red Book 28e
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