Hyphema

Hyphema is a topic covered in the 5-Minute Clinical Consult.

To view the entire topic, please or .

5-Minute Clinical Consult (5MCC) app and website powered by Unbound Medicine helps you diagnose and manage 900+ medical conditions. Exclusive bonus features include Diagnosaurus DDx, 200 pediatrics topics, and medical news feeds. Explore these free sample topics:

-- The first section of this topic is shown below --

Basics

Description

  • A grossly visible collection of blood in the anterior chamber of the eye
  • Microhyphema refers to red blood cells in the anterior chamber which do not layer out and are not grossly visible.
  • Traumatic hyphema is a common complication of blunt or penetrating trauma to the eye that can result in permanent vision loss.

Epidemiology

Incidence
Annual incidence of 20 cases per 100,000 population (1)

Prevalence

  • Up to 70% occur in children with a peak incidence at 10 to 20 years of age.
  • Males are affected 3 to 5 times more often than females (1).

Etiology and Pathophysiology

  • Blunt trauma is the most common cause, and assault is the most common mechanism.
  • Penetrating trauma
  • Postoperatively following intraocular surgery
  • Neoplasm (retinoblastoma or iris melanoma)
  • Clotting disorders (von Willebrand disease or juvenile xanthogranuloma)
    • Pathophysiology: Posterior displacement of tissue stretches the limbal vessels resulting in a tear and lead to bleeding; red blood cells obstruct outflow of aqueous humor and remain in the anterior chamber.

Risk Factors

  • Trauma
  • Congenital bleeding disorders (sickle cell trait or disease)
  • Anticoagulation
  • Intraocular surgery

Commonly Associated Conditions

Blood dyscrasias such as sickle cell disease

-- To view the remaining sections of this topic, please or --

Basics

Description

  • A grossly visible collection of blood in the anterior chamber of the eye
  • Microhyphema refers to red blood cells in the anterior chamber which do not layer out and are not grossly visible.
  • Traumatic hyphema is a common complication of blunt or penetrating trauma to the eye that can result in permanent vision loss.

Epidemiology

Incidence
Annual incidence of 20 cases per 100,000 population (1)

Prevalence

  • Up to 70% occur in children with a peak incidence at 10 to 20 years of age.
  • Males are affected 3 to 5 times more often than females (1).

Etiology and Pathophysiology

  • Blunt trauma is the most common cause, and assault is the most common mechanism.
  • Penetrating trauma
  • Postoperatively following intraocular surgery
  • Neoplasm (retinoblastoma or iris melanoma)
  • Clotting disorders (von Willebrand disease or juvenile xanthogranuloma)
    • Pathophysiology: Posterior displacement of tissue stretches the limbal vessels resulting in a tear and lead to bleeding; red blood cells obstruct outflow of aqueous humor and remain in the anterior chamber.

Risk Factors

  • Trauma
  • Congenital bleeding disorders (sickle cell trait or disease)
  • Anticoagulation
  • Intraocular surgery

Commonly Associated Conditions

Blood dyscrasias such as sickle cell disease

There's more to see -- the rest of this topic is available only to subscribers.