Piperacillin with Tazobactam
Zosyn and generics
Antibiotic, penicillin (extended spectrum with β-lactamase inhibitor)
| B | 2 | Yes | No | No |
| Key |
- 8:1 ratio of piperacillin to tazobactam:
- Injection, powder: 2 g piperacillin and 0.25 g tazobactam; 3 g piperacillin and 0.375 g tazobactam; 4 g piperacillin and 0.5 g tazobactam; 12 g piperacillin and 1.5 g tazobactam; 36 g piperacillin and 4.5 g tazobactam
- Injection, premixed in iso-osmotic dextrose: 2 g piperacillin and 0.25 g tazobactam in 50 mL; 3 g piperacillin and 0.375 g tazobactam in 50 mL; 4 g piperacillin and 0.5 g tazobactam in 100 mL
- Contains 2.84 mEq Na/g piperacillin
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Citation
Hughes, Helen K., and Lauren K. Kahl, editors. "Piperacillin With Tazobactam." Harriet Lane Handbook, 23rd ed., Elsevier, 2024. Harriet Lane, www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309033/2/Piperacillin_with_Tazobactam.
Piperacillin with Tazobactam. In: Hughes HKH, Kahl LKL, eds. Harriet Lane Handbook. Elsevier; 2024. https://www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309033/2/Piperacillin_with_Tazobactam. Accessed October 24, 2026.
Piperacillin with Tazobactam. (2024). In Hughes, H. K., & Kahl, L. K. (Eds.), Harriet Lane Handbook (23rd ed.). Elsevier. https://www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309033/2/Piperacillin_with_Tazobactam
Piperacillin With Tazobactam [Internet]. In: Hughes HKH, Kahl LKL, eds. Harriet Lane Handbook. Elsevier; 2024. [cited 2026 October 24]. Available from: https://www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309033/2/Piperacillin_with_Tazobactam.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Piperacillin with Tazobactam
ID - 309033
ED - Hughes,Helen K,
ED - Kahl,Lauren K,
BT - Harriet Lane Handbook
UR - https://www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309033/2/Piperacillin_with_Tazobactam
PB - Elsevier
ET - 23
DB - Harriet Lane
DP - Unbound Medicine
ER -

Harriet Lane Handbook

