Tobramycin

Tobrex, TOBI, TOBI Podhaler, Bethkis, Kitabis Pak, and generics; previously available as Nebcin
Antibiotic, aminoglycoside

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B/D2YesNoNo
Key
  • Injection: 10 mg/mL (2 mL), 40 mg/mL (2, 30, 50 mL); may contain phenol and bisulfites
  • Powder for injection: 1.2 g; preservative free
  • Ophthalmic ointment (Tobrex): 0.3% (3.5 g); contains 0.5% chlorobutanol
    • In combination with dexamethasone (TobraDex): 0.3% tobramycin with 0.1% dexamethasone (3.5 g); contains 0.5% chlorobutanol
  • Ophthalmic solution (Tobrex and generics): 0.3% (5 mL)
    • In combination with dexamethasone as an ophthalmic suspension (both products contain 0.01% benzalkonium chloride and EDTA):
      • TobraDex and generics: 0.3% tobramycin with 0.1% dexamethasone (2.5, 5, 10 mL)
      • TobraDex ST: 0.3% tobramycin with 0.05% dexamethasone (5 mL)
  • Nebulizer solution:
    • Bethkis: 300 mg/4 mL (56s); preservative free
    • TOBI, Kitabis Pak, and generics: 300 mg/5 mL (56s); preservative free
    • 170 mg/3.4 mL (mixed in 0.45% NS, preservative free, use with eFlow/Trio nebulizer)
  • Powder for inhalation:
    • TOBI Podhaler: 28 mg capsules (224 capsules in 4 weekly packs with 2 Podhaler inhalation devices)

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