Lidocaine
Xylocaine, L-M-X, Lidoderm, Gen7T Plus, many different brands of topical products, and generics
Antiarrhythmic class Ib, local anesthetic
| B | 1 | Yes | Yes | No |
| Key |
- Injection: 0.5%, 1%, 1.5%, 2%, 4% (1% sol ¼ 10 mg/mL)
- IV infusion (in D 5 W): 0.4% (4 mg/mL) (250, 500 mL); 0.8% (8 mg/mL) (250 mL)
- Injection with epinephrine (some preparations may contain metasulfite and parabens or are preservative free):
- Injection with 1:100,000 epinephrine: 1%, 2% lidocaine
- Injection with 1:200,000 epinephrine: 0.5%, 1%, 1.5%, 2% lidocaine
- Ointment: 4% (50 g), 5% (30, 50 g)
- Cream, topical: 3% (30, 85 g), 4% (L-M-X-4 and generics) [OTC] (5, 15, 30, 45 g), 5% (L-M-X-5 and generics) [OTC] (15, 30 g); may contain benzyl alcohol
- Cream, rectal: 5% (L-M-X-5 and others; 15, 30 g); contains benzyl alcohol
- Gel (external): 2% (5, 10, 20, 30 mL), 3% (10, 30 mL), 4% (10, 30 , 113 g), 5% (10, 30, 113 g); may contain benzyl alcohol, EDTA
- Lotion: 3% (118, 177 mL), 4% (88 mL)
- Solution (external): 4% (50 mL); may contain parabens
- Aerosol spray (external): 4% (104 mL)
- Transdermal patch:
- Gen7T Plus and generics: 3.5% (5s, 10s, 15s); may contain menthol
- Lidocaine Pain Relief and generics [OTC]: 4% (5s, 10s); may contain menthol, capsaicin, and methyl salicylate
- Lidoderm and generics: 5% (1s, 15s, 30s)
For explanation of icons, see p. 763 FORMULARY
- Oral solution (mouth/throat): 2% (15, 100 mL), 4% (4 mL)
- Topical cream or gel 2.5% with 2.5% prilocaine: See Lidocaine and Prilocaine.
There's more to see -- the rest of this topic is available only to subscribers.
Citation
Hughes, Helen K., and Lauren K. Kahl, editors. "Lidocaine." Harriet Lane Handbook Harriet Lane Handbook, 23rd ed., Elsevier, 2024. Harriet Lane, www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309183/2/Lidocaine.
Lidocaine. In: Hughes HKH, Kahl LKL, eds. Harriet Lane Handbook Harriet Lane Handbook. Elsevier; 2024. https://www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309183/2/Lidocaine. Accessed October 3, 2026.
Lidocaine. (2024). In Hughes, H. K., & Kahl, L. K. (Eds.), Harriet Lane Handbook Harriet Lane Handbook (23rd ed.). Elsevier. https://www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309183/2/Lidocaine
Lidocaine [Internet]. In: Hughes HKH, Kahl LKL, eds. Harriet Lane Handbook Harriet Lane Handbook. Elsevier; 2024. [cited 2026 October 03]. Available from: https://www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309183/2/Lidocaine.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Lidocaine
ID - 309183
ED - Hughes,Helen K,
ED - Kahl,Lauren K,
BT - Harriet Lane Handbook
UR - https://www.unboundmedicine.com/harrietlane/view/Harriet_Lane_Handbook/309183/2/Lidocaine
PB - Elsevier
ET - 23
DB - Harriet Lane
DP - Unbound Medicine
ER -

Harriet Lane Handbook

