Hyaluronidase

Amphadase, Hylenex, and Vitrase
Antidote, extravasation

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C?NoNoNo
Key
  • Injection:
    • Amphadase: 150 U/mL (1 mL); bovine source; contains edetate disodium and thimerosal
    • Hylenex: 150 U/mL (1 mL); recombinant human source; contains 1 mg albumin, 1.5 mg L-methionine, and 0.2 mg polysorbate 80 per 150 U
    • Vitrase: 200 U/mL (1.2 mL); ovine source containing lactose, preservative free
    • Pharmacy can make a 15 U/mL dilution.

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