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89 results
  • Cardiac Structure and Function in Patients With Obesity and Non-alcoholic Fatty Liver Disease. [Journal Article]
    Cureus. 2023 Aug; 15(8):e43711.Asatullina Z, Sineglazova AV
  • Introduction Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide. The global prevalence of NAFLD is expected to increase dramatically with the increasing prevalence of obesity and type 2 diabetes mellitus (T2DM). The role of NAFLD as a cardiometabolic risk factor or component of metabolic syndrome on the heart remains unclear. Thus, the inde…
  • The Influence of Ketogenic Diet on Gut Microbiota: Potential Benefits, Risks and Indications. [Review]
    Nutrients. 2023 Aug 22; 15(17)Santangelo A, Corsello A, … Peroni DG
  • The ketogenic diet (KD) restricts carbohydrate consumption, leading to an increase in ketone bodies, such as acetoacetate, β-hydroxybutyrate, and acetone, which are utilized as energy substrates. This dietary approach impacts several biochemical processes, resulting in improved clinical management of various disorders, particularly in childhood. However, the exact mechanisms underlying the effica…
  • Childhood nephrotic syndrome. [Review]
    Lancet. 2023 Sep 02; 402(10404):809-824.Vivarelli M, Gibson K, … Boyer O
  • Idiopathic nephrotic syndrome is the most common glomerular disease in children. Corticosteroids are the cornerstone of its treatment, and steroid response is the main prognostic factor. Most children respond to a cycle of oral steroids, and are defined as having steroid-sensitive nephrotic syndrome. Among the children who do not respond, defined as having steroid-resistant nephrotic syndrome, mo…
  • Psilocybin history, action and reaction: A narrative clinical review. [Review]
    J Psychopharmacol. 2023 Sep; 37(9):849-865.Sharma P, Nguyen QA, … Hammond CJ
  • Hallucinogenic mushrooms have been used in religious and cultural ceremonies for centuries. Of late, psilocybin, the psychoactive compound in hallucinogenic mushrooms, has received increased public interest as a novel drug for treating mood and substance use disorders (SUDs). In addition, in recent years, some states in the United States have legalized psilocybin for medical and recreational use.…
  • "It Doesn't Cure, but It Protects": COVID-19 Vaccines through the Eyes of Children and Their Parents. [Journal Article]
    Vaccines (Basel). 2023 Jul 31; 11(8)Groenewald C, Isaacs D, Maluleka M
  • Recently, studies have examined COVID-19 vaccine acceptance and/or hesitancy amongst adult populations across the globe. However, there is a paucity of literature illustrating children's voices in vaccination debates. This article draws on qualitative data collected via a mixed-methods study that explored South Africans' experiences during the COVID-19 pandemic between 2020 and 2021. Interviews w…
  • How Did We Get Here: The Best Vaccines Ever Facing the Highest Public Hesitancy? [Journal Article]
    Vaccines (Basel). 2023 Aug 04; 11(8)Ferreccio C
  • mRNA vaccine technology is the most interesting final product of decades of research. This new platform for public health is simple to transfer to low-income countries and can be used against diverse agents, including cancer. It is environmentally clean, relatively low-cost, and does not use animals for its production. Most importantly, mRNA vaccines have been highly efficacious in avoiding serio…
  • Discovery of phage determinants that confer sensitivity to bacterial immune systems. [Journal Article]
    Cell. 2023 Apr 27; 186(9):1863-1876.e16.Stokar-Avihail A, Fedorenko T, … Sorek R
  • Over the past few years, numerous anti-phage defense systems have been discovered in bacteria. Although the mechanism of defense for some of these systems is understood, a major unanswered question is how these systems sense phage infection. To systematically address this question, we isolated 177 phage mutants that escape 15 different defense systems. In many cases, these escaper phages were mut…
  • StatPearls: Features, Evaluation, and Treatment of Coronavirus (COVID-19) [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)Cascella M, Rajnik M, … Di Napoli RBOOK
  • Coronavirus disease 2019 (COVID-19), the highly contagious viral illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a catastrophic effect on the world’s demographics resulting in more than 3.8 million deaths worldwide, emerging as the most consequential global health crisis since the era of the influenza pandemic of 1918. After the first cases of this predomin…
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