Tags

Type your tag names separated by a space and hit enter

Carriage of GB virus C/hepatitis G virus RNA is associated with a slower immunologic, virologic, and clinical progression of human immunodeficiency virus disease in coinfected persons.
J Infect Dis. 1999 Apr; 179(4):783-9.JI

Abstract

The prevalence of GB virus C (GBV-C) infection is high in human immunodeficiency virus (HIV)-infected persons. However, the long-term consequences of coinfection are unknown. HIV-positive persons with a well-defined duration of infection were screened on the basis of their GBV-C/hepatitis G virus (HGV) RNA status and studied. GBV-C/HGV viremia was observed in 23, who carried the virus over a mean of 7.7 years. All parameters (survival, CDC stage B/C, HIV RNA load, CD4 T cell count) showed significant differences in terms of the cumulative progression rate between persons positive and negative for GBV-C/HGV RNA. When GBV-C/HGV RNA-positive and -unexposed subjects were matched by age, sex, baseline HIV RNA load, and baseline CD4 T cell count, HIV disease progression appeared worse in GBV-C/HGV RNA-negative subjects. The carriage of GBV-C/HGV RNA is associated with a slower progression of HIV disease in coinfected persons.

Authors+Show Affiliations

Institut National de la Transfusion Sanguine, 75012 Paris, France. lefrere@worldnet.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10068572

Citation

Lefrère, J J., et al. "Carriage of GB Virus C/hepatitis G Virus RNA Is Associated With a Slower Immunologic, Virologic, and Clinical Progression of Human Immunodeficiency Virus Disease in Coinfected Persons." The Journal of Infectious Diseases, vol. 179, no. 4, 1999, pp. 783-9.
Lefrère JJ, Roudot-Thoraval F, Morand-Joubert L, et al. Carriage of GB virus C/hepatitis G virus RNA is associated with a slower immunologic, virologic, and clinical progression of human immunodeficiency virus disease in coinfected persons. J Infect Dis. 1999;179(4):783-9.
Lefrère, J. J., Roudot-Thoraval, F., Morand-Joubert, L., Petit, J. C., Lerable, J., Thauvin, M., & Mariotti, M. (1999). Carriage of GB virus C/hepatitis G virus RNA is associated with a slower immunologic, virologic, and clinical progression of human immunodeficiency virus disease in coinfected persons. The Journal of Infectious Diseases, 179(4), 783-9.
Lefrère JJ, et al. Carriage of GB Virus C/hepatitis G Virus RNA Is Associated With a Slower Immunologic, Virologic, and Clinical Progression of Human Immunodeficiency Virus Disease in Coinfected Persons. J Infect Dis. 1999;179(4):783-9. PubMed PMID: 10068572.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carriage of GB virus C/hepatitis G virus RNA is associated with a slower immunologic, virologic, and clinical progression of human immunodeficiency virus disease in coinfected persons. AU - Lefrère,J J, AU - Roudot-Thoraval,F, AU - Morand-Joubert,L, AU - Petit,J C, AU - Lerable,J, AU - Thauvin,M, AU - Mariotti,M, PY - 1999/3/9/pubmed PY - 2000/3/21/medline PY - 1999/3/9/entrez SP - 783 EP - 9 JF - The Journal of infectious diseases JO - J Infect Dis VL - 179 IS - 4 N2 - The prevalence of GB virus C (GBV-C) infection is high in human immunodeficiency virus (HIV)-infected persons. However, the long-term consequences of coinfection are unknown. HIV-positive persons with a well-defined duration of infection were screened on the basis of their GBV-C/hepatitis G virus (HGV) RNA status and studied. GBV-C/HGV viremia was observed in 23, who carried the virus over a mean of 7.7 years. All parameters (survival, CDC stage B/C, HIV RNA load, CD4 T cell count) showed significant differences in terms of the cumulative progression rate between persons positive and negative for GBV-C/HGV RNA. When GBV-C/HGV RNA-positive and -unexposed subjects were matched by age, sex, baseline HIV RNA load, and baseline CD4 T cell count, HIV disease progression appeared worse in GBV-C/HGV RNA-negative subjects. The carriage of GBV-C/HGV RNA is associated with a slower progression of HIV disease in coinfected persons. SN - 0022-1899 UR - https://www.unboundmedicine.com/medline/citation/10068572/Carriage_of_GB_virus_C/hepatitis_G_virus_RNA_is_associated_with_a_slower_immunologic_virologic_and_clinical_progression_of_human_immunodeficiency_virus_disease_in_coinfected_persons_ L2 - https://academic.oup.com/jid/article-lookup/doi/10.1086/314671 DB - PRIME DP - Unbound Medicine ER -