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[Diets enriched with monounsaturated fatty acids and omega-3 polyunsaturated fatty acids decrease blood pressure without changing the plasma insulin concentration in healthy subjects].
Med Clin (Barc) 1999; 112(4):133-7MC

Abstract

BACKGROUND

Plasma glucose, insulin and blood pressure are wellknown cardiovascular risk factors, which may be influence by dietary factors. The aim of the study was to investigate whether changes in dietary fatty acids could modify plasma concentration of glucose, insulin and mean blood pressure (MBP).

SUBJECTS AND METHODS

Forty two subjects (18 women and 24 men) were placed in four consecutive five week diet periods. Energy intake from proteins, carbohydrates and fats was constant during the study and there was only changes on fatty acids composition. First period was enriched on saturated fatty acids (SFA), second period on monounsaturated fatty acids (MUFA) and third and fourth periods were enriched on polyunsaturated fatty acids (PUFA). Fourth period was also enriched on PUFA n-3.

RESULTS

No significant changes were found on glucose and insulin plasma concentration. However, a significant effect was detected on MBP on total population (p < 0.0001) and by gender. MUFA and PUFA n-3 enriched diet decreased significantly MBP compared to SFA enriched diet AGS (85.7, SD 9.1, 87.3, SD 8.7 y 90.3, SD 8.8 mmHg, respectively). In addition, a weak (r = 0.28) but significant (p = 0.002) correlation was found between MBP and plasma insulin.

CONCLUSIONS

Diets enriched on MUFA fatty acids and n-3 fatty acids decrease significantly MBP without modifying glucose and insulin plasma concentration.

Authors+Show Affiliations

Unidad de Investigación en Lípidos, Fundación Jiménez Díaz, Universidad Autónoma de Madrid. lahoz@redestb.esNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

spa

PubMed ID

10074631

Citation

Lahoz, C, et al. "[Diets Enriched With Monounsaturated Fatty Acids and Omega-3 Polyunsaturated Fatty Acids Decrease Blood Pressure Without Changing the Plasma Insulin Concentration in Healthy Subjects]." Medicina Clinica, vol. 112, no. 4, 1999, pp. 133-7.
Lahoz C, Alonso R, Porres A, et al. [Diets enriched with monounsaturated fatty acids and omega-3 polyunsaturated fatty acids decrease blood pressure without changing the plasma insulin concentration in healthy subjects]. Med Clin (Barc). 1999;112(4):133-7.
Lahoz, C., Alonso, R., Porres, A., & Mata, P. (1999). [Diets enriched with monounsaturated fatty acids and omega-3 polyunsaturated fatty acids decrease blood pressure without changing the plasma insulin concentration in healthy subjects]. Medicina Clinica, 112(4), pp. 133-7.
Lahoz C, et al. [Diets Enriched With Monounsaturated Fatty Acids and Omega-3 Polyunsaturated Fatty Acids Decrease Blood Pressure Without Changing the Plasma Insulin Concentration in Healthy Subjects]. Med Clin (Barc). 1999 Feb 6;112(4):133-7. PubMed PMID: 10074631.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Diets enriched with monounsaturated fatty acids and omega-3 polyunsaturated fatty acids decrease blood pressure without changing the plasma insulin concentration in healthy subjects]. AU - Lahoz,C, AU - Alonso,R, AU - Porres,A, AU - Mata,P, PY - 1999/3/13/pubmed PY - 1999/3/13/medline PY - 1999/3/13/entrez SP - 133 EP - 7 JF - Medicina clinica JO - Med Clin (Barc) VL - 112 IS - 4 N2 - BACKGROUND: Plasma glucose, insulin and blood pressure are wellknown cardiovascular risk factors, which may be influence by dietary factors. The aim of the study was to investigate whether changes in dietary fatty acids could modify plasma concentration of glucose, insulin and mean blood pressure (MBP). SUBJECTS AND METHODS: Forty two subjects (18 women and 24 men) were placed in four consecutive five week diet periods. Energy intake from proteins, carbohydrates and fats was constant during the study and there was only changes on fatty acids composition. First period was enriched on saturated fatty acids (SFA), second period on monounsaturated fatty acids (MUFA) and third and fourth periods were enriched on polyunsaturated fatty acids (PUFA). Fourth period was also enriched on PUFA n-3. RESULTS: No significant changes were found on glucose and insulin plasma concentration. However, a significant effect was detected on MBP on total population (p < 0.0001) and by gender. MUFA and PUFA n-3 enriched diet decreased significantly MBP compared to SFA enriched diet AGS (85.7, SD 9.1, 87.3, SD 8.7 y 90.3, SD 8.8 mmHg, respectively). In addition, a weak (r = 0.28) but significant (p = 0.002) correlation was found between MBP and plasma insulin. CONCLUSIONS: Diets enriched on MUFA fatty acids and n-3 fatty acids decrease significantly MBP without modifying glucose and insulin plasma concentration. SN - 0025-7753 UR - https://www.unboundmedicine.com/medline/citation/10074631/[Diets_enriched_with_monounsaturated_fatty_acids_and_omega_3_polyunsaturated_fatty_acids_decrease_blood_pressure_without_changing_the_plasma_insulin_concentration_in_healthy_subjects]_ L2 - http://www.elsevier.es/en/linksolver/ft/ivp/0025-7753/112/133 DB - PRIME DP - Unbound Medicine ER -