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[Sickle cell anemia and pregnancy. Complications and management].
Pathol Biol (Paris). 1999 Jan; 47(1):46-54.PB

Abstract

An increasing number of sickle cell disease patients are deciding to bear children. The high risk of fetal and maternal complications in pregnant sickle cell disease patients mandates multidisciplinary management. Risks include spontaneous abortion, vasculorenal syndrome, fetal growth retardation, and fetal death in utero. The rates of cesarean section, maternofetal infection, and maternal death are higher than in the population at large. The diagnosis should be made prior to conception or during early pregnancy. Frequent visits with the obstetrician, hematologist, and anesthesiologist/intensivist are mandatory. Exchange transfusion or blood transfusion may be indicated in patients with a history of serious obstetrical or hematologic complications. Risks are highest in late pregnancy, during delivery, and in the postpartal period. However, the entire pregnancy is a high-risk period that warrants close monitoring.

Authors+Show Affiliations

Service de Gynécologie-Obstétrique et Médecine de la Reproduction, Hôpital Tenon, Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

10081779

Citation

Berkane, N, et al. "[Sickle Cell Anemia and Pregnancy. Complications and Management]." Pathologie-biologie, vol. 47, no. 1, 1999, pp. 46-54.
Berkane N, Nizard J, Dreux B, et al. [Sickle cell anemia and pregnancy. Complications and management]. Pathol Biol (Paris). 1999;47(1):46-54.
Berkane, N., Nizard, J., Dreux, B., Uzan, S., & Girot, R. (1999). [Sickle cell anemia and pregnancy. Complications and management]. Pathologie-biologie, 47(1), 46-54.
Berkane N, et al. [Sickle Cell Anemia and Pregnancy. Complications and Management]. Pathol Biol (Paris). 1999;47(1):46-54. PubMed PMID: 10081779.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Sickle cell anemia and pregnancy. Complications and management]. AU - Berkane,N, AU - Nizard,J, AU - Dreux,B, AU - Uzan,S, AU - Girot,R, PY - 1999/3/19/pubmed PY - 1999/3/19/medline PY - 1999/3/19/entrez SP - 46 EP - 54 JF - Pathologie-biologie JO - Pathol Biol (Paris) VL - 47 IS - 1 N2 - An increasing number of sickle cell disease patients are deciding to bear children. The high risk of fetal and maternal complications in pregnant sickle cell disease patients mandates multidisciplinary management. Risks include spontaneous abortion, vasculorenal syndrome, fetal growth retardation, and fetal death in utero. The rates of cesarean section, maternofetal infection, and maternal death are higher than in the population at large. The diagnosis should be made prior to conception or during early pregnancy. Frequent visits with the obstetrician, hematologist, and anesthesiologist/intensivist are mandatory. Exchange transfusion or blood transfusion may be indicated in patients with a history of serious obstetrical or hematologic complications. Risks are highest in late pregnancy, during delivery, and in the postpartal period. However, the entire pregnancy is a high-risk period that warrants close monitoring. SN - 0369-8114 UR - https://www.unboundmedicine.com/medline/citation/10081779/[Sickle_cell_anemia_and_pregnancy__Complications_and_management]_ L2 - http://babysfirsttest.org/newborn-screening/conditions/sickle-cell-anemia DB - PRIME DP - Unbound Medicine ER -