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Downward trend in prostate cancer mortality in Quebec and Canada.
J Urol 1999; 161(4):1189-91JU

Abstract

PURPOSE

If new treatment strategies and screening for prostate cancer are effective they should reduce prostate cancer mortality. In this review we monitored prostate cancer mortality rates in Quebec and in Canada.

MATERIALS AND METHODS

We obtained data on all deaths from prostate cancer between 1976 and 1997 in Quebec, and 1976 and 1996 in Canada. We calculated age standardized mortality rates and assessed changes with time.

RESULTS

Prostate cancer mortality rates increased regularly until 1991 in Quebec and Canada. After 1991 the rates decreased moderately until 1995 and then more markedly in 1996. There was a further decline in 1997 in Quebec. Overall, age standardized prostate cancer mortality rates declined by 23% in Quebec between 1991 and 1997, and by 9.6% in Canada between 1991 and 1996. The mortality decline was observed for all age groups but was more pronounced among men younger than 75 years.

CONCLUSIONS

Until 1995 the trends in prostate cancer mortality in Quebec and Canada were similar to those observed in the United States. Our data suggest that a sharper decline has occurred since 1995. It is of primary importance to identify the causes of the mortality decline. As prostate cancer mortality rates declined relatively early after the initiation of widespread screening with prostate specific antigen, it is unlikely that screening has as yet contributed in a major way to the decline. It is more likely that the mortality reduction is a consequence of better prostate cancer management or improved treatment modalities.

Authors+Show Affiliations

Laval University Cancer Research Center, and Department of Social and Preventive Medicine, Laval University, Quebec, Canada.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10081867

Citation

Meyer, F, et al. "Downward Trend in Prostate Cancer Mortality in Quebec and Canada." The Journal of Urology, vol. 161, no. 4, 1999, pp. 1189-91.
Meyer F, Moore L, Bairati I, et al. Downward trend in prostate cancer mortality in Quebec and Canada. J Urol. 1999;161(4):1189-91.
Meyer, F., Moore, L., Bairati, I., & Fradet, Y. (1999). Downward trend in prostate cancer mortality in Quebec and Canada. The Journal of Urology, 161(4), pp. 1189-91.
Meyer F, et al. Downward Trend in Prostate Cancer Mortality in Quebec and Canada. J Urol. 1999;161(4):1189-91. PubMed PMID: 10081867.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Downward trend in prostate cancer mortality in Quebec and Canada. AU - Meyer,F, AU - Moore,L, AU - Bairati,I, AU - Fradet,Y, PY - 1999/3/19/pubmed PY - 1999/3/19/medline PY - 1999/3/19/entrez SP - 1189 EP - 91 JF - The Journal of urology JO - J. Urol. VL - 161 IS - 4 N2 - PURPOSE: If new treatment strategies and screening for prostate cancer are effective they should reduce prostate cancer mortality. In this review we monitored prostate cancer mortality rates in Quebec and in Canada. MATERIALS AND METHODS: We obtained data on all deaths from prostate cancer between 1976 and 1997 in Quebec, and 1976 and 1996 in Canada. We calculated age standardized mortality rates and assessed changes with time. RESULTS: Prostate cancer mortality rates increased regularly until 1991 in Quebec and Canada. After 1991 the rates decreased moderately until 1995 and then more markedly in 1996. There was a further decline in 1997 in Quebec. Overall, age standardized prostate cancer mortality rates declined by 23% in Quebec between 1991 and 1997, and by 9.6% in Canada between 1991 and 1996. The mortality decline was observed for all age groups but was more pronounced among men younger than 75 years. CONCLUSIONS: Until 1995 the trends in prostate cancer mortality in Quebec and Canada were similar to those observed in the United States. Our data suggest that a sharper decline has occurred since 1995. It is of primary importance to identify the causes of the mortality decline. As prostate cancer mortality rates declined relatively early after the initiation of widespread screening with prostate specific antigen, it is unlikely that screening has as yet contributed in a major way to the decline. It is more likely that the mortality reduction is a consequence of better prostate cancer management or improved treatment modalities. SN - 0022-5347 UR - https://www.unboundmedicine.com/medline/citation/10081867/Downward_trend_in_prostate_cancer_mortality_in_Quebec_and_Canada_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-5347(01)61628-8 DB - PRIME DP - Unbound Medicine ER -