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[American pulmonary histoplasmosis caused by Histoplasma capsulatum].
Rev Pneumol Clin. 1998 Dec; 54(6):311-20.RP

Abstract

American pulmonary histoplasmosis is a deep mycosis imported from North America caused by the inhalation of Histoplasma capsulatum. It is endemic in several countries throughout the world and occasional cases have been reported in France, mainly imported from out lying French territories. The most frequent clinical forms observed in immunocompetent subjects are generally benign or silent and usually limited to a fortuitously discovered pulmonary nodule. Massive exposure may lead to an acute primary invasion producing a miliary aspect. Chronic forms simulating tuberculosis are exceptional. Inversely, opportunistic histoplasmosis in AIDS patients can produce an severe multiple organ disease. Ideally, mycelium should be isolated for diagnosis, a task which is easier in disseminated or operated nodular forms. More often, the epidemiological context, clinical and radiological features, the elimination of differential diagnoses and, retrospectively, serology are sufficient for diagnosis. The clinical course is usually favorable. Itraconazole is the treatment of choice for symptomatic or complicated forms.

Authors+Show Affiliations

Service de Pneumologíe, Hôpital d'Instruction des Armées Percy, Clamart.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Review

Language

fre

PubMed ID

10100343

Citation

Guigay, J, et al. "[American Pulmonary Histoplasmosis Caused By Histoplasma Capsulatum]." Revue De Pneumologie Clinique, vol. 54, no. 6, 1998, pp. 311-20.
Guigay J, Cuguillière A, Miltgen J, et al. [American pulmonary histoplasmosis caused by Histoplasma capsulatum]. Rev Pneumol Clin. 1998;54(6):311-20.
Guigay, J., Cuguillière, A., Miltgen, J., Lonjon, T., Jancovici, R., Vaylet, F., Natali, E., Le Vagueresse, R., Bonnet, D., & L'Her, P. (1998). [American pulmonary histoplasmosis caused by Histoplasma capsulatum]. Revue De Pneumologie Clinique, 54(6), 311-20.
Guigay J, et al. [American Pulmonary Histoplasmosis Caused By Histoplasma Capsulatum]. Rev Pneumol Clin. 1998;54(6):311-20. PubMed PMID: 10100343.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [American pulmonary histoplasmosis caused by Histoplasma capsulatum]. AU - Guigay,J, AU - Cuguillière,A, AU - Miltgen,J, AU - Lonjon,T, AU - Jancovici,R, AU - Vaylet,F, AU - Natali,E, AU - Le Vagueresse,R, AU - Bonnet,D, AU - L'Her,P, PY - 1999/4/1/pubmed PY - 1999/4/1/medline PY - 1999/4/1/entrez SP - 311 EP - 20 JF - Revue de pneumologie clinique JO - Rev Pneumol Clin VL - 54 IS - 6 N2 - American pulmonary histoplasmosis is a deep mycosis imported from North America caused by the inhalation of Histoplasma capsulatum. It is endemic in several countries throughout the world and occasional cases have been reported in France, mainly imported from out lying French territories. The most frequent clinical forms observed in immunocompetent subjects are generally benign or silent and usually limited to a fortuitously discovered pulmonary nodule. Massive exposure may lead to an acute primary invasion producing a miliary aspect. Chronic forms simulating tuberculosis are exceptional. Inversely, opportunistic histoplasmosis in AIDS patients can produce an severe multiple organ disease. Ideally, mycelium should be isolated for diagnosis, a task which is easier in disseminated or operated nodular forms. More often, the epidemiological context, clinical and radiological features, the elimination of differential diagnoses and, retrospectively, serology are sufficient for diagnosis. The clinical course is usually favorable. Itraconazole is the treatment of choice for symptomatic or complicated forms. SN - 0761-8417 UR - https://www.unboundmedicine.com/medline/citation/10100343/[American_pulmonary_histoplasmosis_caused_by_Histoplasma_capsulatum]_ L2 - http://www.em-consulte.com/retrieve/pii/MDOI-RP-12-1998-54-6-0761-8417-101019-ART55 DB - PRIME DP - Unbound Medicine ER -