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[Intracranial primitive neuroectodermal tumor in an infant: a case report].
No Shinkei Geka. 1999 Mar; 27(3):243-8.NS

Abstract

A 2-month-old girl with a supratentorial primitive neuroectodermal tumor (PNET), which extended into the skull, is herein presented. The patient underwent total removal of the tumor and also received a course of postoperative chemotherapy. After a follow-up period of 12 months, the infant is alive without recurrence. Histologically, the tumor was composed of poorly differentiated neuroectodermal cells, and these neoplastic cells showed a mild immunohistochemical reaction for GFAP and synaptophysin, and a moderate reactivity for neuron specific enolase and vimentin. In addition, a moderate level of immunoreactivity for HBA71 antigen (p30/32M1C2), which is the product of the M1C2 gene and is found in peripheral PNETs but not in central PNETs, was noted in many neoplastic cells. Although this tumor was located intracranially, it may be classified as a peripheral PNET.

Authors+Show Affiliations

Department of Neurosurgery, Oita Prefectural Hospital, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

jpn

PubMed ID

10190159

Citation

Yoshizato, K, et al. "[Intracranial Primitive Neuroectodermal Tumor in an Infant: a Case Report]." No Shinkei Geka. Neurological Surgery, vol. 27, no. 3, 1999, pp. 243-8.
Yoshizato K, Yoshioka S, Tamai T, et al. [Intracranial primitive neuroectodermal tumor in an infant: a case report]. No Shinkei Geka. 1999;27(3):243-8.
Yoshizato, K., Yoshioka, S., Tamai, T., Tsuji, K., & Nishio, S. (1999). [Intracranial primitive neuroectodermal tumor in an infant: a case report]. No Shinkei Geka. Neurological Surgery, 27(3), 243-8.
Yoshizato K, et al. [Intracranial Primitive Neuroectodermal Tumor in an Infant: a Case Report]. No Shinkei Geka. 1999;27(3):243-8. PubMed PMID: 10190159.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Intracranial primitive neuroectodermal tumor in an infant: a case report]. AU - Yoshizato,K, AU - Yoshioka,S, AU - Tamai,T, AU - Tsuji,K, AU - Nishio,S, PY - 1999/4/6/pubmed PY - 1999/4/6/medline PY - 1999/4/6/entrez SP - 243 EP - 8 JF - No shinkei geka. Neurological surgery JO - No Shinkei Geka VL - 27 IS - 3 N2 - A 2-month-old girl with a supratentorial primitive neuroectodermal tumor (PNET), which extended into the skull, is herein presented. The patient underwent total removal of the tumor and also received a course of postoperative chemotherapy. After a follow-up period of 12 months, the infant is alive without recurrence. Histologically, the tumor was composed of poorly differentiated neuroectodermal cells, and these neoplastic cells showed a mild immunohistochemical reaction for GFAP and synaptophysin, and a moderate reactivity for neuron specific enolase and vimentin. In addition, a moderate level of immunoreactivity for HBA71 antigen (p30/32M1C2), which is the product of the M1C2 gene and is found in peripheral PNETs but not in central PNETs, was noted in many neoplastic cells. Although this tumor was located intracranially, it may be classified as a peripheral PNET. SN - 0301-2603 UR - https://www.unboundmedicine.com/medline/citation/10190159/[Intracranial_primitive_neuroectodermal_tumor_in_an_infant:_a_case_report]_ L2 - https://medlineplus.gov/braintumors.html DB - PRIME DP - Unbound Medicine ER -