Tags

Type your tag names separated by a space and hit enter

Relationship of endogenous circadian melatonin and temperature rhythms to self-reported preference for morning or evening activity in young and older people.
J Investig Med. 1999 Mar; 47(3):141-50.JI

Abstract

BACKGROUND

Morningness-eveningness refers to interindividual differences in preferred timing of behavior (i.e., bed and wake times). Older people have earlier wake times and rate themselves as more morning-like than young adults. It has been reported that the phase of circadian rhythms is earlier in morning-types than in evening types, and that older people have earlier phases than young adults. These changes in phase have been considered to be the chronobiological basis of differences in preferred bed and wake times and age-related changes therein. Whether such differences in phase are associated with changes in the phase relationship between endogenous circadian rhythms and the sleep-wake cycle has not been investigated previously.

METHODS

We investigated the association between circadian phase, the phase relationship between the sleep-wake cycle and circadian rhythms, and morningness-eveningness, and their interaction with aging. In this circadian rhythm study, 68 young and 40 older subjects participated.

RESULTS

Among the young subjects, the phase of the melatonin and core temperature rhythms occurred earlier in morning than in evening types and the interval between circadian phase and usual wake time was longer in morning types. Thus, while evening types woke at a later clock hour than morning types, morning types actually woke at a later circadian phase. Comparing young and older morning types we found that older morning types had an earlier circadian phase and a shorter phase-wake time interval. The shorter phase-waketime interval in older "morning types" is opposite to the change associated with morningness in young people, and is more similar to young evening types.

CONCLUSIONS

These findings demonstrate an association between circadian phase, the relationship between the sleep-wake cycle and circadian phase, and morningness-eveningness in young adults. Furthermore, they demonstrate that age-related changes in phase angle cannot be attributed fully to an age-related shift toward morningness. These findings have important implications for understanding individual preferences in sleep-wake timing and age-related changes in the timing of sleep.

Links

PMC Free PDF
PMC Free Full Text
Publisher Full Text

Authors+Show Affiliations

Duffy JF
Department of Medicine, Brigham & Women's Hospital, Boston, MA 02115-5817, USA.
Dijk DJ
No affiliation info available
Hall EF
No affiliation info available
Czeisler CA
No affiliation info available

MeSH

AdolescentAdultAgedAged, 80 and overAgingBody TemperatureCircadian RhythmHumansMelatoninMiddle AgedPolysomnographySleepSurveys and Questionnaires

Pub Type(s)

Comparative Study
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

10198570

Citation

Duffy, J F., et al. "Relationship of Endogenous Circadian Melatonin and Temperature Rhythms to Self-reported Preference for Morning or Evening Activity in Young and Older People." Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research, vol. 47, no. 3, 1999, pp. 141-50.
Duffy JF, Dijk DJ, Hall EF, et al. Relationship of endogenous circadian melatonin and temperature rhythms to self-reported preference for morning or evening activity in young and older people. J Investig Med. 1999;47(3):141-50.
Duffy, J. F., Dijk, D. J., Hall, E. F., & Czeisler, C. A. (1999). Relationship of endogenous circadian melatonin and temperature rhythms to self-reported preference for morning or evening activity in young and older people. Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research, 47(3), 141-50.
Duffy JF, et al. Relationship of Endogenous Circadian Melatonin and Temperature Rhythms to Self-reported Preference for Morning or Evening Activity in Young and Older People. J Investig Med. 1999;47(3):141-50. PubMed PMID: 10198570.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship of endogenous circadian melatonin and temperature rhythms to self-reported preference for morning or evening activity in young and older people. AU - Duffy,J F, AU - Dijk,D J, AU - Hall,E F, AU - Czeisler,C A, PY - 1999/4/13/pubmed PY - 1999/4/13/medline PY - 1999/4/13/entrez KW - NASA Discipline Regulatory Physiology KW - Non-NASA Center SP - 141 EP - 50 JF - Journal of investigative medicine : the official publication of the American Federation for Clinical Research JO - J Investig Med VL - 47 IS - 3 N2 - BACKGROUND: Morningness-eveningness refers to interindividual differences in preferred timing of behavior (i.e., bed and wake times). Older people have earlier wake times and rate themselves as more morning-like than young adults. It has been reported that the phase of circadian rhythms is earlier in morning-types than in evening types, and that older people have earlier phases than young adults. These changes in phase have been considered to be the chronobiological basis of differences in preferred bed and wake times and age-related changes therein. Whether such differences in phase are associated with changes in the phase relationship between endogenous circadian rhythms and the sleep-wake cycle has not been investigated previously. METHODS: We investigated the association between circadian phase, the phase relationship between the sleep-wake cycle and circadian rhythms, and morningness-eveningness, and their interaction with aging. In this circadian rhythm study, 68 young and 40 older subjects participated. RESULTS: Among the young subjects, the phase of the melatonin and core temperature rhythms occurred earlier in morning than in evening types and the interval between circadian phase and usual wake time was longer in morning types. Thus, while evening types woke at a later clock hour than morning types, morning types actually woke at a later circadian phase. Comparing young and older morning types we found that older morning types had an earlier circadian phase and a shorter phase-wake time interval. The shorter phase-waketime interval in older "morning types" is opposite to the change associated with morningness in young people, and is more similar to young evening types. CONCLUSIONS: These findings demonstrate an association between circadian phase, the relationship between the sleep-wake cycle and circadian phase, and morningness-eveningness in young adults. Furthermore, they demonstrate that age-related changes in phase angle cannot be attributed fully to an age-related shift toward morningness. These findings have important implications for understanding individual preferences in sleep-wake timing and age-related changes in the timing of sleep. SN - 1081-5589 UR - https://www.unboundmedicine.com/medline/citation/10198570/Relationship_of_endogenous_circadian_melatonin_and_temperature_rhythms_to_self_reported_preference_for_morning_or_evening_activity_in_young_and_older_people_ L2 - https://jim.bmj.com/lookup/pmidlookup?view=long&pmid=10198570 DB - PRIME DP - Unbound Medicine ER -