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In vitro dialyzability using meal approach as an index for zinc and iron absorption in humans.
Biol Trace Elem Res 1999; 67(3):249-56BT

Abstract

With a standardized protocol under simulated gastrointestinal conditions, 65Zn and 59Fe dialyzability was measured for 38 diets from 7 different published studies on human absorption. The compositions of these diets were available in the form of the amounts of food ingredients used for breakfast, lunch, and dinner. Considering each of these types as a separate meal, percent dialyzability was measured. The weighted average of breakfast, lunch, dinner, and snacks, if any, was taken to represent the entire day's bioavailability. The correlation between in vitro percent dialyzability and reported human absorption was 0.92 for zinc and 0.96 for iron and both were statistically significant (p = 0.0001). The prediction equations for zinc and iron were obtained as y = -0.7718 + 1.1038x and y = 0.3197 + 0.9084x, respectively. This indicated that in vitro dialyzability using the meal approach can be used as an index with good discriminating power for different levels of human absorption.

Authors+Show Affiliations

Biometry and Nutrition Group, Agharkar Research Institute, Pune, India.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10201331

Citation

Chiplonkar, S A., et al. "In Vitro Dialyzability Using Meal Approach as an Index for Zinc and Iron Absorption in Humans." Biological Trace Element Research, vol. 67, no. 3, 1999, pp. 249-56.
Chiplonkar SA, Agte VV, Tarwadi KV, et al. In vitro dialyzability using meal approach as an index for zinc and iron absorption in humans. Biol Trace Elem Res. 1999;67(3):249-56.
Chiplonkar, S. A., Agte, V. V., Tarwadi, K. V., & Kavadia, R. (1999). In vitro dialyzability using meal approach as an index for zinc and iron absorption in humans. Biological Trace Element Research, 67(3), pp. 249-56.
Chiplonkar SA, et al. In Vitro Dialyzability Using Meal Approach as an Index for Zinc and Iron Absorption in Humans. Biol Trace Elem Res. 1999;67(3):249-56. PubMed PMID: 10201331.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro dialyzability using meal approach as an index for zinc and iron absorption in humans. AU - Chiplonkar,S A, AU - Agte,V V, AU - Tarwadi,K V, AU - Kavadia,R, PY - 1999/4/14/pubmed PY - 1999/4/14/medline PY - 1999/4/14/entrez SP - 249 EP - 56 JF - Biological trace element research JO - Biol Trace Elem Res VL - 67 IS - 3 N2 - With a standardized protocol under simulated gastrointestinal conditions, 65Zn and 59Fe dialyzability was measured for 38 diets from 7 different published studies on human absorption. The compositions of these diets were available in the form of the amounts of food ingredients used for breakfast, lunch, and dinner. Considering each of these types as a separate meal, percent dialyzability was measured. The weighted average of breakfast, lunch, dinner, and snacks, if any, was taken to represent the entire day's bioavailability. The correlation between in vitro percent dialyzability and reported human absorption was 0.92 for zinc and 0.96 for iron and both were statistically significant (p = 0.0001). The prediction equations for zinc and iron were obtained as y = -0.7718 + 1.1038x and y = 0.3197 + 0.9084x, respectively. This indicated that in vitro dialyzability using the meal approach can be used as an index with good discriminating power for different levels of human absorption. SN - 0163-4984 UR - https://www.unboundmedicine.com/medline/citation/10201331/In_vitro_dialyzability_using_meal_approach_as_an_index_for_zinc_and_iron_absorption_in_humans_ L2 - https://dx.doi.org/10.1007/BF02784424 DB - PRIME DP - Unbound Medicine ER -