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Prevalence of heart failure and left ventricular dysfunction in the general population; The Rotterdam Study.
Eur Heart J 1999; 20(6):447-55EH

Abstract

AIMS

To determine the prevalence of heart failure and symptomatic as well as asymptomatic left ventricular systolic dysfunction in the general population.

METHODS AND RESULTS

In 5540 participants of the Rotterdam Study (age 68.9+/-8.7 years, 2251 men) aged 55-95 years, the presence of heart failure was determined by assessment of symptoms and signs (shortness of breath. ankle oedema and pulmonary crepitations) and use of heart failure medication. In 2267 subjects (age 65.7+/-7.4 years, 1028 men) fractional shortening was measured. The overall prevalence of heart failure was 3.9% (95% CI 3.0+/-4.7) and did not differ between men and women. The prevalence increased with age, with the exception of the highest age group in men. Fractional shortening was higher in women and did not decrease appreciably with age. The prevalence of left ventricular systolic dysfunction (fractional shortening <=25%) was approximately 2.5 times higher in men (5.5%, 95% CI 4.1-7.0) than in women (2.2%, 95% CI 1.4-3.2). Sixty percent of persons with left ventricular systolic dysfunction had no symptoms or signs of heart failure at all.

CONCLUSIONS

The prevalence of heart failure is appreciable and does not differ between men and women. The majority of persons with left ventricular systolic dysfunction can be regarded as having asymptomatic left ventricular systolic dysfunction.

Authors+Show Affiliations

Department of Epidemiology & Biostatistics, Erasmus University and University Hospital Rotterdam Dijkzigt, The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10213348

Citation

Mosterd, A, et al. "Prevalence of Heart Failure and Left Ventricular Dysfunction in the General Population; the Rotterdam Study." European Heart Journal, vol. 20, no. 6, 1999, pp. 447-55.
Mosterd A, Hoes AW, de Bruyne MC, et al. Prevalence of heart failure and left ventricular dysfunction in the general population; The Rotterdam Study. Eur Heart J. 1999;20(6):447-55.
Mosterd, A., Hoes, A. W., de Bruyne, M. C., Deckers, J. W., Linker, D. T., Hofman, A., & Grobbee, D. E. (1999). Prevalence of heart failure and left ventricular dysfunction in the general population; The Rotterdam Study. European Heart Journal, 20(6), pp. 447-55.
Mosterd A, et al. Prevalence of Heart Failure and Left Ventricular Dysfunction in the General Population; the Rotterdam Study. Eur Heart J. 1999;20(6):447-55. PubMed PMID: 10213348.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of heart failure and left ventricular dysfunction in the general population; The Rotterdam Study. AU - Mosterd,A, AU - Hoes,A W, AU - de Bruyne,M C, AU - Deckers,J W, AU - Linker,D T, AU - Hofman,A, AU - Grobbee,D E, PY - 1999/4/23/pubmed PY - 1999/4/23/medline PY - 1999/4/23/entrez SP - 447 EP - 55 JF - European heart journal JO - Eur. Heart J. VL - 20 IS - 6 N2 - AIMS: To determine the prevalence of heart failure and symptomatic as well as asymptomatic left ventricular systolic dysfunction in the general population. METHODS AND RESULTS: In 5540 participants of the Rotterdam Study (age 68.9+/-8.7 years, 2251 men) aged 55-95 years, the presence of heart failure was determined by assessment of symptoms and signs (shortness of breath. ankle oedema and pulmonary crepitations) and use of heart failure medication. In 2267 subjects (age 65.7+/-7.4 years, 1028 men) fractional shortening was measured. The overall prevalence of heart failure was 3.9% (95% CI 3.0+/-4.7) and did not differ between men and women. The prevalence increased with age, with the exception of the highest age group in men. Fractional shortening was higher in women and did not decrease appreciably with age. The prevalence of left ventricular systolic dysfunction (fractional shortening <=25%) was approximately 2.5 times higher in men (5.5%, 95% CI 4.1-7.0) than in women (2.2%, 95% CI 1.4-3.2). Sixty percent of persons with left ventricular systolic dysfunction had no symptoms or signs of heart failure at all. CONCLUSIONS: The prevalence of heart failure is appreciable and does not differ between men and women. The majority of persons with left ventricular systolic dysfunction can be regarded as having asymptomatic left ventricular systolic dysfunction. SN - 0195-668X UR - https://www.unboundmedicine.com/medline/citation/10213348/Prevalence_of_heart_failure_and_left_ventricular_dysfunction_in_the_general_population L2 - https://medlineplus.gov/heartfailure.html DB - PRIME DP - Unbound Medicine ER -