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Abdominal symptoms are not related to anorectal function in the irritable bowel syndrome.
Scand J Gastroenterol 1999; 34(3):250-8SJ

Abstract

BACKGROUND

The pathophysiologic significance of altered intestinal motility and perception in irritable bowel syndrome (IBS) is unclear, as a consistent association with abdominal symptoms has not been proved. Our aim was to investigate the association between abdominal symptoms and anorectal function in IBS.

METHODS

Fifty-two patients recorded their symptoms daily for I week. At the end of the week anorectal function was investigated by manovolumetry before and after a standardized fatty meal. Cluster analysis of daily recorded symptoms and both pre- and postprandial manovolumetric data was performed to identify symptom and physiologic subgroups.

RESULTS

Symptom subgroups did not differ with regard to anorectal function. Physiologic subgroups did not differ with regard to daily recorded symptoms. Postprandially, the thresholds eliciting maximal tolerable distention were decreased in 22 of the patients. This increase in rectal sensitivity was not related to symptoms and may have been caused by the preprandial anorectal measurement, since thresholds for maximal tolerable distention decreased significantly in nine patients retested without an intervening meal.

CONCLUSIONS

Abdominal symptoms and anorectal function are not related in IBS.

Authors+Show Affiliations

Department of Health and Environment, Faculty of Health Sciences, Linköping University, Sweden.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10232868

Citation

Ragnarsson, G, et al. "Abdominal Symptoms Are Not Related to Anorectal Function in the Irritable Bowel Syndrome." Scandinavian Journal of Gastroenterology, vol. 34, no. 3, 1999, pp. 250-8.
Ragnarsson G, Hallböök O, Bodemar G. Abdominal symptoms are not related to anorectal function in the irritable bowel syndrome. Scand J Gastroenterol. 1999;34(3):250-8.
Ragnarsson, G., Hallböök, O., & Bodemar, G. (1999). Abdominal symptoms are not related to anorectal function in the irritable bowel syndrome. Scandinavian Journal of Gastroenterology, 34(3), pp. 250-8.
Ragnarsson G, Hallböök O, Bodemar G. Abdominal Symptoms Are Not Related to Anorectal Function in the Irritable Bowel Syndrome. Scand J Gastroenterol. 1999;34(3):250-8. PubMed PMID: 10232868.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Abdominal symptoms are not related to anorectal function in the irritable bowel syndrome. AU - Ragnarsson,G, AU - Hallböök,O, AU - Bodemar,G, PY - 1999/5/8/pubmed PY - 1999/5/8/medline PY - 1999/5/8/entrez SP - 250 EP - 8 JF - Scandinavian journal of gastroenterology JO - Scand. J. Gastroenterol. VL - 34 IS - 3 N2 - BACKGROUND: The pathophysiologic significance of altered intestinal motility and perception in irritable bowel syndrome (IBS) is unclear, as a consistent association with abdominal symptoms has not been proved. Our aim was to investigate the association between abdominal symptoms and anorectal function in IBS. METHODS: Fifty-two patients recorded their symptoms daily for I week. At the end of the week anorectal function was investigated by manovolumetry before and after a standardized fatty meal. Cluster analysis of daily recorded symptoms and both pre- and postprandial manovolumetric data was performed to identify symptom and physiologic subgroups. RESULTS: Symptom subgroups did not differ with regard to anorectal function. Physiologic subgroups did not differ with regard to daily recorded symptoms. Postprandially, the thresholds eliciting maximal tolerable distention were decreased in 22 of the patients. This increase in rectal sensitivity was not related to symptoms and may have been caused by the preprandial anorectal measurement, since thresholds for maximal tolerable distention decreased significantly in nine patients retested without an intervening meal. CONCLUSIONS: Abdominal symptoms and anorectal function are not related in IBS. SN - 0036-5521 UR - https://www.unboundmedicine.com/medline/citation/10232868/Abdominal_symptoms_are_not_related_to_anorectal_function_in_the_irritable_bowel_syndrome_ L2 - http://www.tandfonline.com/doi/full/10.1080/00365529950173645 DB - PRIME DP - Unbound Medicine ER -