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Nickel allergy and its relationship with local nickel pollution, ear piercing, and atopic dermatitis: a population-based study from Norway.
J Am Acad Dermatol 1999; 40(5 Pt 1):726-35JA

Abstract

BACKGROUND

The north-Norwegian population of Sør-Varanger lives close to 2 Russian nickel smelters.

OBJECTIVE

We studied the importance of the local nickel pollution, as well as ear piercing and atopic dermatitis, on the prevalence of nickel allergy in Sør-Varanger.

METHODS

We patch-tested 1767 adults who were randomly selected from 2 different cross-sectional studies; in Sør-Varanger and the reference city of Tromsø, which has no nickel-polluting industry.

RESULTS

Nickel allergy was diagnosed in 27.5% and 31.1% of the women in Sør-Varanger and Tromsø, respectively, and in 5.1% and 5.0% of the men. In women, ear piercing was a strong risk factor (relative risk = 3.30; 95% confidence interval = 2.01 to 5.43). A history of atopic dermatitis was not associated with nickel sensitization. We found no increased risk of nickel allergy in Sør-Varanger compared with Tromsø in adjusted multivariate analyses.

CONCLUSION

The high prevalence of nickel allergy found in Sør-Varanger could not be attributed to pollution from the nearby nickel industry.

Authors+Show Affiliations

Institute of Community Medicine, University of Tromsø, Norway.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10321601

Citation

Smith-Sivertsen, T, et al. "Nickel Allergy and Its Relationship With Local Nickel Pollution, Ear Piercing, and Atopic Dermatitis: a Population-based Study From Norway." Journal of the American Academy of Dermatology, vol. 40, no. 5 Pt 1, 1999, pp. 726-35.
Smith-Sivertsen T, Dotterud LK, Lund E. Nickel allergy and its relationship with local nickel pollution, ear piercing, and atopic dermatitis: a population-based study from Norway. J Am Acad Dermatol. 1999;40(5 Pt 1):726-35.
Smith-Sivertsen, T., Dotterud, L. K., & Lund, E. (1999). Nickel allergy and its relationship with local nickel pollution, ear piercing, and atopic dermatitis: a population-based study from Norway. Journal of the American Academy of Dermatology, 40(5 Pt 1), pp. 726-35.
Smith-Sivertsen T, Dotterud LK, Lund E. Nickel Allergy and Its Relationship With Local Nickel Pollution, Ear Piercing, and Atopic Dermatitis: a Population-based Study From Norway. J Am Acad Dermatol. 1999;40(5 Pt 1):726-35. PubMed PMID: 10321601.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nickel allergy and its relationship with local nickel pollution, ear piercing, and atopic dermatitis: a population-based study from Norway. AU - Smith-Sivertsen,T, AU - Dotterud,L K, AU - Lund,E, PY - 1999/5/13/pubmed PY - 1999/5/13/medline PY - 1999/5/13/entrez SP - 726 EP - 35 JF - Journal of the American Academy of Dermatology JO - J. Am. Acad. Dermatol. VL - 40 IS - 5 Pt 1 N2 - BACKGROUND: The north-Norwegian population of Sør-Varanger lives close to 2 Russian nickel smelters. OBJECTIVE: We studied the importance of the local nickel pollution, as well as ear piercing and atopic dermatitis, on the prevalence of nickel allergy in Sør-Varanger. METHODS: We patch-tested 1767 adults who were randomly selected from 2 different cross-sectional studies; in Sør-Varanger and the reference city of Tromsø, which has no nickel-polluting industry. RESULTS: Nickel allergy was diagnosed in 27.5% and 31.1% of the women in Sør-Varanger and Tromsø, respectively, and in 5.1% and 5.0% of the men. In women, ear piercing was a strong risk factor (relative risk = 3.30; 95% confidence interval = 2.01 to 5.43). A history of atopic dermatitis was not associated with nickel sensitization. We found no increased risk of nickel allergy in Sør-Varanger compared with Tromsø in adjusted multivariate analyses. CONCLUSION: The high prevalence of nickel allergy found in Sør-Varanger could not be attributed to pollution from the nearby nickel industry. SN - 0190-9622 UR - https://www.unboundmedicine.com/medline/citation/10321601/Nickel_allergy_and_its_relationship_with_local_nickel_pollution_ear_piercing_and_atopic_dermatitis:_a_population_based_study_from_Norway_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0190-9622(99)70154-4 DB - PRIME DP - Unbound Medicine ER -