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Cardiovascular disease risk factors in young children in the STRIP baby project. Special Turku coronary Risk factor Intervention Project for children.
Ann Med 1999; 31 Suppl 1:55-61AM

Abstract

Introducing nutritional principles of preventive cardiology to the care of young children may improve permanently adherence to a low-saturated-fat, low-cholesterol diet later in life. This approach has not been readily adapted because of worries of the possible effects of such a diet on the growth and development of children. In the STRIP baby project, 1062 infants were randomized at 7 months of age into an intervention group (n = 540) or a control group (n = 522). The counselling of the intervention children aimed at a fat intake of 30% of energy after the age of 1 year and to a 1:1:1 ratio in saturated:monounsaturated:polyunsaturated fat intake. Dietary intake, growth and serum lipid concentrations were monitored in the children regularly through the first years of life. The intake of total fat, saturated fat and cholesterol were lower and the intake of polyunsaturated fat and the ratio of polyunsaturated to saturated fat (P/S) in the diet were higher in the intervention children than in the controls. During the first 3 years of the trial, the serum cholesterol concentration was 3-6% lower in the intervention children than in the controls (95% CI for the mean difference between groups from -0.27 to -0.12 mmol/L). No differences in the growth of the children were observed between the groups. We conclude that repeated individualized counselling aiming at reduced consumption of saturated fat combined with regular follow-up is effective and does not restrict the growth of children.

Authors+Show Affiliations

Department of Paediatrics, University of Turku, Finland. olli.simell@utu.fi

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10342501

Citation

Simell, O, et al. "Cardiovascular Disease Risk Factors in Young Children in the STRIP Baby Project. Special Turku Coronary Risk Factor Intervention Project for Children." Annals of Medicine, vol. 31 Suppl 1, 1999, pp. 55-61.
Simell O, Niinikoski H, Viikari J, et al. Cardiovascular disease risk factors in young children in the STRIP baby project. Special Turku coronary Risk factor Intervention Project for children. Ann Med. 1999;31 Suppl 1:55-61.
Simell, O., Niinikoski, H., Viikari, J., Rask-Nissilä, L., Tammi, A., & Rönnemaa, T. (1999). Cardiovascular disease risk factors in young children in the STRIP baby project. Special Turku coronary Risk factor Intervention Project for children. Annals of Medicine, 31 Suppl 1, pp. 55-61.
Simell O, et al. Cardiovascular Disease Risk Factors in Young Children in the STRIP Baby Project. Special Turku Coronary Risk Factor Intervention Project for Children. Ann Med. 1999;31 Suppl 1:55-61. PubMed PMID: 10342501.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cardiovascular disease risk factors in young children in the STRIP baby project. Special Turku coronary Risk factor Intervention Project for children. AU - Simell,O, AU - Niinikoski,H, AU - Viikari,J, AU - Rask-Nissilä,L, AU - Tammi,A, AU - Rönnemaa,T, PY - 1999/5/26/pubmed PY - 1999/5/26/medline PY - 1999/5/26/entrez SP - 55 EP - 61 JF - Annals of medicine JO - Ann. Med. VL - 31 Suppl 1 N2 - Introducing nutritional principles of preventive cardiology to the care of young children may improve permanently adherence to a low-saturated-fat, low-cholesterol diet later in life. This approach has not been readily adapted because of worries of the possible effects of such a diet on the growth and development of children. In the STRIP baby project, 1062 infants were randomized at 7 months of age into an intervention group (n = 540) or a control group (n = 522). The counselling of the intervention children aimed at a fat intake of 30% of energy after the age of 1 year and to a 1:1:1 ratio in saturated:monounsaturated:polyunsaturated fat intake. Dietary intake, growth and serum lipid concentrations were monitored in the children regularly through the first years of life. The intake of total fat, saturated fat and cholesterol were lower and the intake of polyunsaturated fat and the ratio of polyunsaturated to saturated fat (P/S) in the diet were higher in the intervention children than in the controls. During the first 3 years of the trial, the serum cholesterol concentration was 3-6% lower in the intervention children than in the controls (95% CI for the mean difference between groups from -0.27 to -0.12 mmol/L). No differences in the growth of the children were observed between the groups. We conclude that repeated individualized counselling aiming at reduced consumption of saturated fat combined with regular follow-up is effective and does not restrict the growth of children. SN - 0785-3890 UR - https://www.unboundmedicine.com/medline/citation/10342501/Cardiovascular_disease_risk_factors_in_young_children_in_the_STRIP_baby_project__Special_Turku_coronary_Risk_factor_Intervention_Project_for_children_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=10342501.ui DB - PRIME DP - Unbound Medicine ER -