Tags

Type your tag names separated by a space and hit enter

[Effective nasal CPAP therapy for heavy snoring and paradoxical respiration during sleep in a case of multiple system atrophy].
Rinsho Shinkeigaku. 1998 Dec; 38(12):1059-63.RS

Abstract

A 64-year-old man with multiple system atrophy complained of daytime sleepiness, fatigue, and snoring. Neurological examination revealed severe autonomic failure, mild cerebellar ataxia and akinesia. Daytime blood gas analysis showed respiratory acidosis with hypoxia and hypercapnia. MR imaging of the brain showed atrophy of the pons, cerebellum and bilateral frontal lobes. Although paralysis of the vocal cord abduction was not found by laryngoscopy during daytime examination, polysomnography (PSG) showed heavy snoring with paradoxical respiration associated with severe desaturation during sleep as well as reduced slow wave sleep and REM sleep. He was diagnosed as having sleep-related upper airway obstructive breathing disorder probably due to Gerhardt syndrome. Tracheostomy was considered, but we performed nasal CPAP therapy during sleep because this therapy is non-invasive and would not impair his daily life. After nasal CPAP therapy, daytime sleepiness, fatigue, and snoring with desaturation improved, and PSG showed increased slow wave sleep. These results demonstrate that nasal CPAP therapy improves the quality of sleep and should be considered in patients with early stages of multiple system atrophy who exhibit sleep-related breathing disorders.

Authors+Show Affiliations

Department of Neurology, Dokkyo University School of Medicine, Tochigi, Japan.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article
Review

Language

jpn

PubMed ID

10349349

Citation

Miyamoto, M, et al. "[Effective Nasal CPAP Therapy for Heavy Snoring and Paradoxical Respiration During Sleep in a Case of Multiple System Atrophy]." Rinsho Shinkeigaku = Clinical Neurology, vol. 38, no. 12, 1998, pp. 1059-63.
Miyamoto M, Miyamoto T, Katayama S, et al. [Effective nasal CPAP therapy for heavy snoring and paradoxical respiration during sleep in a case of multiple system atrophy]. Rinsho Shinkeigaku. 1998;38(12):1059-63.
Miyamoto, M., Miyamoto, T., Katayama, S., & Hirata, K. (1998). [Effective nasal CPAP therapy for heavy snoring and paradoxical respiration during sleep in a case of multiple system atrophy]. Rinsho Shinkeigaku = Clinical Neurology, 38(12), 1059-63.
Miyamoto M, et al. [Effective Nasal CPAP Therapy for Heavy Snoring and Paradoxical Respiration During Sleep in a Case of Multiple System Atrophy]. Rinsho Shinkeigaku. 1998;38(12):1059-63. PubMed PMID: 10349349.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effective nasal CPAP therapy for heavy snoring and paradoxical respiration during sleep in a case of multiple system atrophy]. AU - Miyamoto,M, AU - Miyamoto,T, AU - Katayama,S, AU - Hirata,K, PY - 1999/6/1/pubmed PY - 1999/6/1/medline PY - 1999/6/1/entrez SP - 1059 EP - 63 JF - Rinsho shinkeigaku = Clinical neurology JO - Rinsho Shinkeigaku VL - 38 IS - 12 N2 - A 64-year-old man with multiple system atrophy complained of daytime sleepiness, fatigue, and snoring. Neurological examination revealed severe autonomic failure, mild cerebellar ataxia and akinesia. Daytime blood gas analysis showed respiratory acidosis with hypoxia and hypercapnia. MR imaging of the brain showed atrophy of the pons, cerebellum and bilateral frontal lobes. Although paralysis of the vocal cord abduction was not found by laryngoscopy during daytime examination, polysomnography (PSG) showed heavy snoring with paradoxical respiration associated with severe desaturation during sleep as well as reduced slow wave sleep and REM sleep. He was diagnosed as having sleep-related upper airway obstructive breathing disorder probably due to Gerhardt syndrome. Tracheostomy was considered, but we performed nasal CPAP therapy during sleep because this therapy is non-invasive and would not impair his daily life. After nasal CPAP therapy, daytime sleepiness, fatigue, and snoring with desaturation improved, and PSG showed increased slow wave sleep. These results demonstrate that nasal CPAP therapy improves the quality of sleep and should be considered in patients with early stages of multiple system atrophy who exhibit sleep-related breathing disorders. SN - 0009-918X UR - https://www.unboundmedicine.com/medline/citation/10349349/[Effective_nasal_CPAP_therapy_for_heavy_snoring_and_paradoxical_respiration_during_sleep_in_a_case_of_multiple_system_atrophy]_ L2 - http://www.diseaseinfosearch.org/result/4975 DB - PRIME DP - Unbound Medicine ER -