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Antiandrogen treatment of polycystic ovary syndrome.
Endocrinol Metab Clin North Am. 1999 Jun; 28(2):409-21.EM

Abstract

Although hirsutism and androgenetic alopecia are cosmetic problems, they can be psychologically devastating for women. Mechanical hair removal may control the cosmetic appearance of hirsutism, but the underlying problem usually continues to progress. Topical therapies for androgenetic alopecia provide for modest improvement at best, and no topical therapy has been shown to be effective for hirsutism. Antiandrogens, combined with ovarian suppression, offer the best hope for the improvement of hirsutism and androgenetic alopecia in women with PCOS. Improvement will occur in most women. Unless the underlying cause of the PCOS is corrected, medical therapy will need to be continued indefinitely.

Authors+Show Affiliations

Glaxo Wellcome Research and Development, Research Triangle Park, North Carolina, USA. rsr89794@glaxowellcome.com

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

10352926

Citation

Rittmaster, R S.. "Antiandrogen Treatment of Polycystic Ovary Syndrome." Endocrinology and Metabolism Clinics of North America, vol. 28, no. 2, 1999, pp. 409-21.
Rittmaster RS. Antiandrogen treatment of polycystic ovary syndrome. Endocrinol Metab Clin North Am. 1999;28(2):409-21.
Rittmaster, R. S. (1999). Antiandrogen treatment of polycystic ovary syndrome. Endocrinology and Metabolism Clinics of North America, 28(2), 409-21.
Rittmaster RS. Antiandrogen Treatment of Polycystic Ovary Syndrome. Endocrinol Metab Clin North Am. 1999;28(2):409-21. PubMed PMID: 10352926.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antiandrogen treatment of polycystic ovary syndrome. A1 - Rittmaster,R S, PY - 1999/6/3/pubmed PY - 1999/6/3/medline PY - 1999/6/3/entrez SP - 409 EP - 21 JF - Endocrinology and metabolism clinics of North America JO - Endocrinol Metab Clin North Am VL - 28 IS - 2 N2 - Although hirsutism and androgenetic alopecia are cosmetic problems, they can be psychologically devastating for women. Mechanical hair removal may control the cosmetic appearance of hirsutism, but the underlying problem usually continues to progress. Topical therapies for androgenetic alopecia provide for modest improvement at best, and no topical therapy has been shown to be effective for hirsutism. Antiandrogens, combined with ovarian suppression, offer the best hope for the improvement of hirsutism and androgenetic alopecia in women with PCOS. Improvement will occur in most women. Unless the underlying cause of the PCOS is corrected, medical therapy will need to be continued indefinitely. SN - 0889-8529 UR - https://www.unboundmedicine.com/medline/citation/10352926/Antiandrogen_treatment_of_polycystic_ovary_syndrome_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0889-8529(05)70077-3 DB - PRIME DP - Unbound Medicine ER -