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Alcohol intake, beverage preference, and risk of hip fracture in men and women. Copenhagen Centre for Prospective Population Studies.
Am J Epidemiol 1999; 149(11):993-1001AJ

Abstract

The authors prospectively studied the association between quantity and type of alcohol intake and risk of hip fracture among 17,868 men and 13,917 women. Analyses were based on pooled data from three population studies conducted in 1964-1992 in Copenhagen, Denmark. During follow-up, 500 first hip fractures were identified in women and 307 in men. A low to moderate weekly alcohol intake (1-27 drinks for men and 1-13 drinks for women) was not associated with hip fracture. Among men, the relative risk of hip fracture gradually increased for those who drank 28 drinks or more per week (relative risk (RR) = 1.75, 95% confidence interval (CI) 1.06-2.89 for 28-41 drinks; RR = 5.28, 95% CI 2.60-10.70 for 70 or more drinks) as compared with abstainers. Women who drank 14-27 drinks per week had an age-adjusted relative risk of hip fracture of 1.44 (95% CI 1.03-2.03), but the association weakened after adjustment for confounders (RR = 1.32, 95% CI 0.92-1.87). The risk of hip fracture differed according to the type of alcohol preferred: preferrers of beer had a higher risk of hip fracture (RR = 1.46, 95% CI 1.11-1.91) than preferrers of other types of alcoholic beverages. The corresponding relative risks for preferrers of wine and spirits were 0.77 (95% CI 0.58-1.03) and 0.82 (95% CI 0.58-1.14), respectively. In conclusion, an alcohol intake within the current European drinking limits does not influence the risk of hip fracture, whereas an alcohol intake of more than 27 drinks per week is a major risk factor for men.

Authors+Show Affiliations

Danish Epidemiology Science Centre, Institute of Preventive Medicine, Copenhagen University Hospital.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10355374

Citation

Høidrup, S, et al. "Alcohol Intake, Beverage Preference, and Risk of Hip Fracture in Men and Women. Copenhagen Centre for Prospective Population Studies." American Journal of Epidemiology, vol. 149, no. 11, 1999, pp. 993-1001.
Høidrup S, Grønbaek M, Gottschau A, et al. Alcohol intake, beverage preference, and risk of hip fracture in men and women. Copenhagen Centre for Prospective Population Studies. Am J Epidemiol. 1999;149(11):993-1001.
Høidrup, S., Grønbaek, M., Gottschau, A., Lauritzen, J. B., & Schroll, M. (1999). Alcohol intake, beverage preference, and risk of hip fracture in men and women. Copenhagen Centre for Prospective Population Studies. American Journal of Epidemiology, 149(11), pp. 993-1001.
Høidrup S, et al. Alcohol Intake, Beverage Preference, and Risk of Hip Fracture in Men and Women. Copenhagen Centre for Prospective Population Studies. Am J Epidemiol. 1999 Jun 1;149(11):993-1001. PubMed PMID: 10355374.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alcohol intake, beverage preference, and risk of hip fracture in men and women. Copenhagen Centre for Prospective Population Studies. AU - Høidrup,S, AU - Grønbaek,M, AU - Gottschau,A, AU - Lauritzen,J B, AU - Schroll,M, PY - 1999/6/4/pubmed PY - 1999/6/4/medline PY - 1999/6/4/entrez SP - 993 EP - 1001 JF - American journal of epidemiology JO - Am. J. Epidemiol. VL - 149 IS - 11 N2 - The authors prospectively studied the association between quantity and type of alcohol intake and risk of hip fracture among 17,868 men and 13,917 women. Analyses were based on pooled data from three population studies conducted in 1964-1992 in Copenhagen, Denmark. During follow-up, 500 first hip fractures were identified in women and 307 in men. A low to moderate weekly alcohol intake (1-27 drinks for men and 1-13 drinks for women) was not associated with hip fracture. Among men, the relative risk of hip fracture gradually increased for those who drank 28 drinks or more per week (relative risk (RR) = 1.75, 95% confidence interval (CI) 1.06-2.89 for 28-41 drinks; RR = 5.28, 95% CI 2.60-10.70 for 70 or more drinks) as compared with abstainers. Women who drank 14-27 drinks per week had an age-adjusted relative risk of hip fracture of 1.44 (95% CI 1.03-2.03), but the association weakened after adjustment for confounders (RR = 1.32, 95% CI 0.92-1.87). The risk of hip fracture differed according to the type of alcohol preferred: preferrers of beer had a higher risk of hip fracture (RR = 1.46, 95% CI 1.11-1.91) than preferrers of other types of alcoholic beverages. The corresponding relative risks for preferrers of wine and spirits were 0.77 (95% CI 0.58-1.03) and 0.82 (95% CI 0.58-1.14), respectively. In conclusion, an alcohol intake within the current European drinking limits does not influence the risk of hip fracture, whereas an alcohol intake of more than 27 drinks per week is a major risk factor for men. SN - 0002-9262 UR - https://www.unboundmedicine.com/medline/citation/10355374/Alcohol_intake_beverage_preference_and_risk_of_hip_fracture_in_men_and_women__Copenhagen_Centre_for_Prospective_Population_Studies_ L2 - https://academic.oup.com/aje/article-lookup/doi/10.1093/oxfordjournals.aje.a009760 DB - PRIME DP - Unbound Medicine ER -