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Catheter mounted coaxially moveable ablation electrode for the creation of linear transmural endocardial lesions.
J Cardiovasc Electrophysiol. 1999 Apr; 10(4):566-73.JC

Abstract

INTRODUCTION

Use of a novel ablation catheter for the creation of linear transmural endocardial lesions, which uses a coaxially moving ablation electrode mounted on the terminal portion of a catheter shaft and able to move axially for a distance of up to 4 cm, is reported.

METHODS AND RESULTS

The coaxially moving ablation electrode is moved by a sliding mechanism in the catheter handle. The distal portion of the catheter shaft is steerable. Bipolar or unipolar electrograms can be recorded from electrodes on the catheter tip and the coaxially moving ablation. Radiofrequency (RF) current is delivered to the coaxially moving ablation electrode with thermocouple temperature control. This ablation catheter was evaluated in five (30 to 65 kg) anesthetized pigs and introduced via the venous/arterial systems into the right and left atrium (1 lesion) (using the retrograde aortic approach). The catheter was maneuvered to bring the slide range into apposition with atrial endocardium. The coaxially moving ablation electrode was deployed to the terminal portion of the catheter's slide range and then withdrawn in 2-mm steps. RF current was delivered to the coaxially moving ablation electrode at each point (maximum temperature 70 degrees C). Postmortem examination of eight endocardial linear lesions (2.2 to 4.1 cm length) was made 1 to 3 hours after creation. Histopathologic examination confirmed transmural myocyte necrosis along the length of the lesion, that included the trabeculated right atrium.

CONCLUSION

We conclude that a catheter using a moveable electrode creates continuous linear transmural lesions and could find clinical application in the therapy of a variety of reentry tachycardia mechanisms.

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Authors+Show Affiliations

Morgan JM
Wessex Cardiothoracic Center, Southampton University Hospital, United Kingdom. JMM@cardiology.co.uk
Roberts PR
No affiliation info available
Allen S
No affiliation info available
Gallagher PJ
No affiliation info available
Gibson C
No affiliation info available
Cunningham AD
No affiliation info available

MeSH

AnimalsCardiac CatheterizationCatheter AblationDisease Models, AnimalElectrocardiographyElectrodesEndocardiumFemaleHeart AtriaHeart Conduction SystemNecrosisSwine

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

10355699

Citation

Morgan, J M., et al. "Catheter Mounted Coaxially Moveable Ablation Electrode for the Creation of Linear Transmural Endocardial Lesions." Journal of Cardiovascular Electrophysiology, vol. 10, no. 4, 1999, pp. 566-73.
Morgan JM, Roberts PR, Allen S, et al. Catheter mounted coaxially moveable ablation electrode for the creation of linear transmural endocardial lesions. J Cardiovasc Electrophysiol. 1999;10(4):566-73.
Morgan, J. M., Roberts, P. R., Allen, S., Gallagher, P. J., Gibson, C., & Cunningham, A. D. (1999). Catheter mounted coaxially moveable ablation electrode for the creation of linear transmural endocardial lesions. Journal of Cardiovascular Electrophysiology, 10(4), 566-73.
Morgan JM, et al. Catheter Mounted Coaxially Moveable Ablation Electrode for the Creation of Linear Transmural Endocardial Lesions. J Cardiovasc Electrophysiol. 1999;10(4):566-73. PubMed PMID: 10355699.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Catheter mounted coaxially moveable ablation electrode for the creation of linear transmural endocardial lesions. AU - Morgan,J M, AU - Roberts,P R, AU - Allen,S, AU - Gallagher,P J, AU - Gibson,C, AU - Cunningham,A D, PY - 1999/6/4/pubmed PY - 1999/6/4/medline PY - 1999/6/4/entrez SP - 566 EP - 73 JF - Journal of cardiovascular electrophysiology JO - J Cardiovasc Electrophysiol VL - 10 IS - 4 N2 - INTRODUCTION: Use of a novel ablation catheter for the creation of linear transmural endocardial lesions, which uses a coaxially moving ablation electrode mounted on the terminal portion of a catheter shaft and able to move axially for a distance of up to 4 cm, is reported. METHODS AND RESULTS: The coaxially moving ablation electrode is moved by a sliding mechanism in the catheter handle. The distal portion of the catheter shaft is steerable. Bipolar or unipolar electrograms can be recorded from electrodes on the catheter tip and the coaxially moving ablation. Radiofrequency (RF) current is delivered to the coaxially moving ablation electrode with thermocouple temperature control. This ablation catheter was evaluated in five (30 to 65 kg) anesthetized pigs and introduced via the venous/arterial systems into the right and left atrium (1 lesion) (using the retrograde aortic approach). The catheter was maneuvered to bring the slide range into apposition with atrial endocardium. The coaxially moving ablation electrode was deployed to the terminal portion of the catheter's slide range and then withdrawn in 2-mm steps. RF current was delivered to the coaxially moving ablation electrode at each point (maximum temperature 70 degrees C). Postmortem examination of eight endocardial linear lesions (2.2 to 4.1 cm length) was made 1 to 3 hours after creation. Histopathologic examination confirmed transmural myocyte necrosis along the length of the lesion, that included the trabeculated right atrium. CONCLUSION: We conclude that a catheter using a moveable electrode creates continuous linear transmural lesions and could find clinical application in the therapy of a variety of reentry tachycardia mechanisms. SN - 1045-3873 UR - https://www.unboundmedicine.com/medline/citation/10355699/Catheter_mounted_coaxially_moveable_ablation_electrode_for_the_creation_of_linear_transmural_endocardial_lesions_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1045-3873&date=1999&volume=10&issue=4&spage=566 DB - PRIME DP - Unbound Medicine ER -