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SAPHO syndrome of the temporomandibular joint associated with sudden deafness.
AJNR Am J Neuroradiol 1999; 20(5):902-5AA

Abstract

We report a case of arthritis of the temporomandibular joint (TMJ) associated with sclerosing osteomyelitis of the mandible and temporal bone, causing deafness. The presence of a palmoplantar pustulosis established the diagnosis of SAPHO syndrome. SAPHO (an acronym referring to synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis) syndrome is defined by the association of characteristic osteoarticular and dermatologic manifestations, with diffuse sclerosing osteomyelitis of the mandible being a part of this entity. We review the literature of SAPHO syndrome with mandibular manifestations and discuss the mechanisms of inflammatory spread from the TMJ to the cochlea. To our knowledge, this is the first description of skull base involvement in a patient with SAPHO syndrome leading to sudden deafness.

Authors+Show Affiliations

Department of Radiology, University Hospital St Antoine, Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

10369364

Citation

Marsot-Dupuch, K, et al. "SAPHO Syndrome of the Temporomandibular Joint Associated With Sudden Deafness." AJNR. American Journal of Neuroradiology, vol. 20, no. 5, 1999, pp. 902-5.
Marsot-Dupuch K, Doyen JE, Grauer WO, et al. SAPHO syndrome of the temporomandibular joint associated with sudden deafness. AJNR Am J Neuroradiol. 1999;20(5):902-5.
Marsot-Dupuch, K., Doyen, J. E., Grauer, W. O., & de Givry, S. C. (1999). SAPHO syndrome of the temporomandibular joint associated with sudden deafness. AJNR. American Journal of Neuroradiology, 20(5), pp. 902-5.
Marsot-Dupuch K, et al. SAPHO Syndrome of the Temporomandibular Joint Associated With Sudden Deafness. AJNR Am J Neuroradiol. 1999;20(5):902-5. PubMed PMID: 10369364.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - SAPHO syndrome of the temporomandibular joint associated with sudden deafness. AU - Marsot-Dupuch,K, AU - Doyen,J E, AU - Grauer,W O, AU - de Givry,S C, PY - 1999/6/16/pubmed PY - 1999/6/16/medline PY - 1999/6/16/entrez SP - 902 EP - 5 JF - AJNR. American journal of neuroradiology JO - AJNR Am J Neuroradiol VL - 20 IS - 5 N2 - We report a case of arthritis of the temporomandibular joint (TMJ) associated with sclerosing osteomyelitis of the mandible and temporal bone, causing deafness. The presence of a palmoplantar pustulosis established the diagnosis of SAPHO syndrome. SAPHO (an acronym referring to synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis) syndrome is defined by the association of characteristic osteoarticular and dermatologic manifestations, with diffuse sclerosing osteomyelitis of the mandible being a part of this entity. We review the literature of SAPHO syndrome with mandibular manifestations and discuss the mechanisms of inflammatory spread from the TMJ to the cochlea. To our knowledge, this is the first description of skull base involvement in a patient with SAPHO syndrome leading to sudden deafness. SN - 0195-6108 UR - https://www.unboundmedicine.com/medline/citation/10369364/SAPHO_syndrome_of_the_temporomandibular_joint_associated_with_sudden_deafness_ L2 - http://www.ajnr.org/cgi/pmidlookup?view=long&pmid=10369364 DB - PRIME DP - Unbound Medicine ER -