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Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis.
Mayo Clin Proc 1999; 74(6):575-8MC

Abstract

An opportunistic infection is a known, although under-diagnosed, complication of systemic lupus erythematosus (SLE). A 48-year-old woman with a recent diagnosis of SLE was admitted to the hospital because of a fever, confused state, and convulsive episode. Her symptoms were interpreted as being compatible with lupus cerebritis. Treatment with methylprednisolone resulted in a temporary improvement in the patient's condition. Nevertheless, during the next few weeks, her physical and mental condition deteriorated, and she died of massive pulmonary emboli. An autopsy revealed no signs of lupus cerebritis; however, disseminated cerebral toxoplasmosis was found. Cerebral toxoplasmosis is a rare complication of SLE that may be misdiagnosed as lupus cerebritis.

Authors+Show Affiliations

Department of Medicine, Hillel Yaffe Medical Center, Hadera, Israel.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

10377932

Citation

Zamir, D, et al. "Toxoplasma Infection in Systemic Lupus Erythematosus Mimicking Lupus Cerebritis." Mayo Clinic Proceedings, vol. 74, no. 6, 1999, pp. 575-8.
Zamir D, Amar M, Groisman G, et al. Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis. Mayo Clin Proc. 1999;74(6):575-8.
Zamir, D., Amar, M., Groisman, G., & Weiner, P. (1999). Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis. Mayo Clinic Proceedings, 74(6), pp. 575-8.
Zamir D, et al. Toxoplasma Infection in Systemic Lupus Erythematosus Mimicking Lupus Cerebritis. Mayo Clin Proc. 1999;74(6):575-8. PubMed PMID: 10377932.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis. AU - Zamir,D, AU - Amar,M, AU - Groisman,G, AU - Weiner,P, PY - 1999/6/23/pubmed PY - 1999/6/23/medline PY - 1999/6/23/entrez SP - 575 EP - 8 JF - Mayo Clinic proceedings JO - Mayo Clin. Proc. VL - 74 IS - 6 N2 - An opportunistic infection is a known, although under-diagnosed, complication of systemic lupus erythematosus (SLE). A 48-year-old woman with a recent diagnosis of SLE was admitted to the hospital because of a fever, confused state, and convulsive episode. Her symptoms were interpreted as being compatible with lupus cerebritis. Treatment with methylprednisolone resulted in a temporary improvement in the patient's condition. Nevertheless, during the next few weeks, her physical and mental condition deteriorated, and she died of massive pulmonary emboli. An autopsy revealed no signs of lupus cerebritis; however, disseminated cerebral toxoplasmosis was found. Cerebral toxoplasmosis is a rare complication of SLE that may be misdiagnosed as lupus cerebritis. SN - 0025-6196 UR - https://www.unboundmedicine.com/medline/citation/10377932/Toxoplasma_infection_in_systemic_lupus_erythematosus_mimicking_lupus_cerebritis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0025-6196(11)64133-5 DB - PRIME DP - Unbound Medicine ER -