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Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis.

Abstract

An opportunistic infection is a known, although under-diagnosed, complication of systemic lupus erythematosus (SLE). A 48-year-old woman with a recent diagnosis of SLE was admitted to the hospital because of a fever, confused state, and convulsive episode. Her symptoms were interpreted as being compatible with lupus cerebritis. Treatment with methylprednisolone resulted in a temporary improvement in the patient's condition. Nevertheless, during the next few weeks, her physical and mental condition deteriorated, and she died of massive pulmonary emboli. An autopsy revealed no signs of lupus cerebritis; however, disseminated cerebral toxoplasmosis was found. Cerebral toxoplasmosis is a rare complication of SLE that may be misdiagnosed as lupus cerebritis.

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  • Authors+Show Affiliations

    ,

    Department of Medicine, Hillel Yaffe Medical Center, Hadera, Israel.

    , ,

    Source

    Mayo Clinic proceedings 74:6 1999 Jun pg 575-8

    MeSH

    Autopsy
    Diagnosis, Differential
    Fatal Outcome
    Female
    Humans
    Lupus Erythematosus, Systemic
    Middle Aged
    Opportunistic Infections
    Toxoplasmosis, Cerebral

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    10377932

    Citation

    Zamir, D, et al. "Toxoplasma Infection in Systemic Lupus Erythematosus Mimicking Lupus Cerebritis." Mayo Clinic Proceedings, vol. 74, no. 6, 1999, pp. 575-8.
    Zamir D, Amar M, Groisman G, et al. Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis. Mayo Clin Proc. 1999;74(6):575-8.
    Zamir, D., Amar, M., Groisman, G., & Weiner, P. (1999). Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis. Mayo Clinic Proceedings, 74(6), pp. 575-8.
    Zamir D, et al. Toxoplasma Infection in Systemic Lupus Erythematosus Mimicking Lupus Cerebritis. Mayo Clin Proc. 1999;74(6):575-8. PubMed PMID: 10377932.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Toxoplasma infection in systemic lupus erythematosus mimicking lupus cerebritis. AU - Zamir,D, AU - Amar,M, AU - Groisman,G, AU - Weiner,P, PY - 1999/6/23/pubmed PY - 1999/6/23/medline PY - 1999/6/23/entrez SP - 575 EP - 8 JF - Mayo Clinic proceedings JO - Mayo Clin. Proc. VL - 74 IS - 6 N2 - An opportunistic infection is a known, although under-diagnosed, complication of systemic lupus erythematosus (SLE). A 48-year-old woman with a recent diagnosis of SLE was admitted to the hospital because of a fever, confused state, and convulsive episode. Her symptoms were interpreted as being compatible with lupus cerebritis. Treatment with methylprednisolone resulted in a temporary improvement in the patient's condition. Nevertheless, during the next few weeks, her physical and mental condition deteriorated, and she died of massive pulmonary emboli. An autopsy revealed no signs of lupus cerebritis; however, disseminated cerebral toxoplasmosis was found. Cerebral toxoplasmosis is a rare complication of SLE that may be misdiagnosed as lupus cerebritis. SN - 0025-6196 UR - https://www.unboundmedicine.com/medline/citation/10377932/Toxoplasma_infection_in_systemic_lupus_erythematosus_mimicking_lupus_cerebritis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0025-6196(11)64133-5 DB - PRIME DP - Unbound Medicine ER -