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Comparative efficacy of three measles vaccines in Indian children.
Indian J Public Health. 1998 Oct-Dec; 42(4):113-9.IJ

Abstract

A Comparative study of three types of measles vaccines was undertaken among 1005 children. Of these 527 were vaccinated with the Serum Institute of India (SII) vaccine, 230 with Schwarz (SC) and 248 were vaccinated with Edmonston-Zegreb (EZ) vaccine (imported from Zegreb). Though the majority of children reacted favourably with all the three vaccines (SII: 98.43%; SC: 93.40%; EZ: 93.0%) with a rise in titre, but the percentage of seroconversion was significantly higher with the SII vaccine (p < 0.01). The Schwarz and Edmonston Zagreb vaccines showed significantly less GM titre as compared with the other age group i.e. 9-12 months (p < 0.05). With Serum Institute of India (SII) vaccine the GM titres were almost similar in the different age groups. The overall GM titre obtained with the SII vaccine was significantly higher than the SC vaccine (p > 0.001) as well as the EZ vaccine (p > 0.001). It is of interest to note that among the infants, 22.5% children had measles antibody in them before vaccination.

Authors+Show Affiliations

National Institute of Virology, Pune.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

10389523

Citation

Banerjee, K, et al. "Comparative Efficacy of Three Measles Vaccines in Indian Children." Indian Journal of Public Health, vol. 42, no. 4, 1998, pp. 113-9.
Banerjee K, Shaikh N, Phadke M, et al. Comparative efficacy of three measles vaccines in Indian children. Indian J Public Health. 1998;42(4):113-9.
Banerjee, K., Shaikh, N., Phadke, M., Bedekar, S. S., Rauta, S. K., & Mehta, J. M. (1998). Comparative efficacy of three measles vaccines in Indian children. Indian Journal of Public Health, 42(4), 113-9.
Banerjee K, et al. Comparative Efficacy of Three Measles Vaccines in Indian Children. Indian J Public Health. 1998 Oct-Dec;42(4):113-9. PubMed PMID: 10389523.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparative efficacy of three measles vaccines in Indian children. AU - Banerjee,K, AU - Shaikh,N, AU - Phadke,M, AU - Bedekar,S S, AU - Rauta,S K, AU - Mehta,J M, PY - 1999/7/2/pubmed PY - 1999/7/2/medline PY - 1999/7/2/entrez KW - Age Factors KW - Asia KW - Child KW - Clinical Research KW - Comparative Studies KW - Demographic Factors KW - Developing Countries KW - Diseases KW - India KW - Measles--prevention and control KW - Population KW - Population Characteristics KW - Research Methodology KW - Research Report KW - Southern Asia KW - Studies KW - Vaccines KW - Viral Diseases KW - Youth SP - 113 EP - 9 JF - Indian journal of public health JO - Indian J Public Health VL - 42 IS - 4 N2 - A Comparative study of three types of measles vaccines was undertaken among 1005 children. Of these 527 were vaccinated with the Serum Institute of India (SII) vaccine, 230 with Schwarz (SC) and 248 were vaccinated with Edmonston-Zegreb (EZ) vaccine (imported from Zegreb). Though the majority of children reacted favourably with all the three vaccines (SII: 98.43%; SC: 93.40%; EZ: 93.0%) with a rise in titre, but the percentage of seroconversion was significantly higher with the SII vaccine (p < 0.01). The Schwarz and Edmonston Zagreb vaccines showed significantly less GM titre as compared with the other age group i.e. 9-12 months (p < 0.05). With Serum Institute of India (SII) vaccine the GM titres were almost similar in the different age groups. The overall GM titre obtained with the SII vaccine was significantly higher than the SC vaccine (p > 0.001) as well as the EZ vaccine (p > 0.001). It is of interest to note that among the infants, 22.5% children had measles antibody in them before vaccination. SN - 0019-557X UR - https://www.unboundmedicine.com/medline/citation/10389523/Comparative_efficacy_of_three_measles_vaccines_in_Indian_children_ L2 - http://www.diseaseinfosearch.org/result/4535 DB - PRIME DP - Unbound Medicine ER -