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Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO consultation criteria, and 1985 WHO criteria. World Health Organization.
Diabetes Res Clin Pract. 1999 Apr; 44(1):21-6.DR

Abstract

To compare 1997 ADA diagnostic criteria for diabetes mellitus and other categories of glucose intolerance/1998 WHO Consultation criteria versus 1985 WHO criteria, we analyzed data from a 75-g oral glucose tolerance test (OGTT) performed on 1051 high-risk subjects without medical history of diabetes at Diabetes Screening Clinic, Ramathibodi Hospital, Thailand. There were 372 males and 679 females, aged (mean +/- S.D.) = 50.3 +/- 12.55 years, BMI = 25.62 +/- 4.39 kg/m2. If fasting plasma glucose (FPG) was used as recently recommended then 54.1, 20.4, and 25.5% of cases were classified as normal, impaired fasting glucose (IFG), and diabetic, respectively. In diagnosing diabetes using a full OGTT based on the 1985 WHO criteria as the reference test, FPG > or = 7 mmol/l had a sensitivity of 57.7%, specificity of 97.4%, positive predictive value of 94.0%, and negative predictive value of 76.4%; 53.7% of subjects with IFG had 2-h plasma glucose > or = 11.1 mmol/l. The 1997 ADA/1998 WHO Consultation criteria and 1985 WHO criteria for a full OGTT yield similar overall results. FPG (> or = 7 mmol/l) was not sensitive for diagnosing diabetes. Moreover, about half of the subjects with IFG were actually diabetic. Therefore, OGTT remains a valuable test in diagnosing diabetes and classifying various categories of glucose intolerance.

Authors+Show Affiliations

Department of Medicine and Research Center, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

10414936

Citation

Puavilai, G, et al. "Diagnostic Criteria for Diabetes Mellitus and Other Categories of Glucose Intolerance: 1997 Criteria By the Expert Committee On the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO Consultation Criteria, and 1985 WHO Criteria. World Health Organization." Diabetes Research and Clinical Practice, vol. 44, no. 1, 1999, pp. 21-6.
Puavilai G, Chanprasertyotin S, Sriphrapradaeng A. Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO consultation criteria, and 1985 WHO criteria. World Health Organization. Diabetes Res Clin Pract. 1999;44(1):21-6.
Puavilai, G., Chanprasertyotin, S., & Sriphrapradaeng, A. (1999). Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO consultation criteria, and 1985 WHO criteria. World Health Organization. Diabetes Research and Clinical Practice, 44(1), 21-6.
Puavilai G, Chanprasertyotin S, Sriphrapradaeng A. Diagnostic Criteria for Diabetes Mellitus and Other Categories of Glucose Intolerance: 1997 Criteria By the Expert Committee On the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO Consultation Criteria, and 1985 WHO Criteria. World Health Organization. Diabetes Res Clin Pract. 1999;44(1):21-6. PubMed PMID: 10414936.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnostic criteria for diabetes mellitus and other categories of glucose intolerance: 1997 criteria by the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (ADA), 1998 WHO consultation criteria, and 1985 WHO criteria. World Health Organization. AU - Puavilai,G, AU - Chanprasertyotin,S, AU - Sriphrapradaeng,A, PY - 1999/7/22/pubmed PY - 1999/7/22/medline PY - 1999/7/22/entrez SP - 21 EP - 6 JF - Diabetes research and clinical practice JO - Diabetes Res Clin Pract VL - 44 IS - 1 N2 - To compare 1997 ADA diagnostic criteria for diabetes mellitus and other categories of glucose intolerance/1998 WHO Consultation criteria versus 1985 WHO criteria, we analyzed data from a 75-g oral glucose tolerance test (OGTT) performed on 1051 high-risk subjects without medical history of diabetes at Diabetes Screening Clinic, Ramathibodi Hospital, Thailand. There were 372 males and 679 females, aged (mean +/- S.D.) = 50.3 +/- 12.55 years, BMI = 25.62 +/- 4.39 kg/m2. If fasting plasma glucose (FPG) was used as recently recommended then 54.1, 20.4, and 25.5% of cases were classified as normal, impaired fasting glucose (IFG), and diabetic, respectively. In diagnosing diabetes using a full OGTT based on the 1985 WHO criteria as the reference test, FPG > or = 7 mmol/l had a sensitivity of 57.7%, specificity of 97.4%, positive predictive value of 94.0%, and negative predictive value of 76.4%; 53.7% of subjects with IFG had 2-h plasma glucose > or = 11.1 mmol/l. The 1997 ADA/1998 WHO Consultation criteria and 1985 WHO criteria for a full OGTT yield similar overall results. FPG (> or = 7 mmol/l) was not sensitive for diagnosing diabetes. Moreover, about half of the subjects with IFG were actually diabetic. Therefore, OGTT remains a valuable test in diagnosing diabetes and classifying various categories of glucose intolerance. SN - 0168-8227 UR - https://www.unboundmedicine.com/medline/citation/10414936/Diagnostic_criteria_for_diabetes_mellitus_and_other_categories_of_glucose_intolerance:_1997_criteria_by_the_Expert_Committee_on_the_Diagnosis_and_Classification_of_Diabetes_Mellitus__ADA__1998_WHO_consultation_criteria_and_1985_WHO_criteria__World_Health_Organization_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S016882279900008X DB - PRIME DP - Unbound Medicine ER -