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[Leukokoria in a child: emergency and challenge].

Abstract

PURPOSE

To heighten the awareness of the medical world to the importance of correct and rapid diagnosis in the presence of leukocoria in the child.

METHODS

Starting with the presenting symptom, the authors present the guide lines to follow in a practical manner in order to reach a diagnosis in the principal retinal diseases causing leukocoria.

RESULTS

A white pupil is due to retinoblastoma in almost half of all cases. Other possible causes, in order of frequency, are: persistent hyperplastic primary vitreous, Coats' disease, ocular toxocariasis, retinopathy of prematurity, retinal hamartomas. Diagnosis can usually readily be made by ophthalmoscopy, but may be problematic when the clinical presentation is atypical or in the presence of late complications. Age, sex, laterality, heredity, and in particular the presence or absence of calcifications and the size of the globe, are the main criteria for diagnosis. Ultrasonography plays a major role in this essential quest for correct diagnosis, quest which may ultimately lead to enucleation.

CONCLUSION

Leukocoria in the child is a danger signal demanding certain diagnosis within the shortest possible time.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Hôpital Ophtalmique Jules Gonin, Université de Lausanne.

    Source

    MeSH

    Child
    Child, Preschool
    Diagnosis, Differential
    Emergencies
    Female
    Humans
    Infant
    Male
    Retinal Neoplasms
    Retinoblastoma
    Ultrasonography

    Pub Type(s)

    English Abstract
    Journal Article
    Review

    Language

    fre

    PubMed ID

    10420380

    Citation

    Balmer, A, and F Munier. "[Leukokoria in a Child: Emergency and Challenge]." Klinische Monatsblatter Fur Augenheilkunde, vol. 214, no. 5, 1999, pp. 332-5.
    Balmer A, Munier F. [Leukokoria in a child: emergency and challenge]. Klin Monbl Augenheilkd. 1999;214(5):332-5.
    Balmer, A., & Munier, F. (1999). [Leukokoria in a child: emergency and challenge]. Klinische Monatsblatter Fur Augenheilkunde, 214(5), pp. 332-5.
    Balmer A, Munier F. [Leukokoria in a Child: Emergency and Challenge]. Klin Monbl Augenheilkd. 1999;214(5):332-5. PubMed PMID: 10420380.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - [Leukokoria in a child: emergency and challenge]. AU - Balmer,A, AU - Munier,F, PY - 1999/7/27/pubmed PY - 1999/7/27/medline PY - 1999/7/27/entrez SP - 332 EP - 5 JF - Klinische Monatsblatter fur Augenheilkunde JO - Klin Monbl Augenheilkd VL - 214 IS - 5 N2 - PURPOSE: To heighten the awareness of the medical world to the importance of correct and rapid diagnosis in the presence of leukocoria in the child. METHODS: Starting with the presenting symptom, the authors present the guide lines to follow in a practical manner in order to reach a diagnosis in the principal retinal diseases causing leukocoria. RESULTS: A white pupil is due to retinoblastoma in almost half of all cases. Other possible causes, in order of frequency, are: persistent hyperplastic primary vitreous, Coats' disease, ocular toxocariasis, retinopathy of prematurity, retinal hamartomas. Diagnosis can usually readily be made by ophthalmoscopy, but may be problematic when the clinical presentation is atypical or in the presence of late complications. Age, sex, laterality, heredity, and in particular the presence or absence of calcifications and the size of the globe, are the main criteria for diagnosis. Ultrasonography plays a major role in this essential quest for correct diagnosis, quest which may ultimately lead to enucleation. CONCLUSION: Leukocoria in the child is a danger signal demanding certain diagnosis within the shortest possible time. SN - 0023-2165 UR - https://www.unboundmedicine.com/medline/citation/10420380/[Leukokoria_in_a_child:_emergency_and_challenge] L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2008-1034807 DB - PRIME DP - Unbound Medicine ER -