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[Measles, mumps and rubella: vaccination rate and seroprevalence in 8th grade students of 8 different sites in Switzerland 1995/96].
Praxis (Bern 1994). 1999 Jun 10; 88(24):1069-77.P

Abstract

In 1987, the Swiss Federal Health Office (BAG) and the Swiss cantons launched the MMR-vaccination campaign. Within the frame of the SCARPOL Study, the vaccination status of 649, 8th class students was registered and serum samples were collected. The measles, mumps and rubella specific antibody levels were determined. The vaccination rate was 84% for measles, 74% for mumps, and 62% for rubella, 55% of these children had been vaccinated with the combined vaccine MMR. The vaccination rate for the different study areas varied from 70% to 95% for measles, 42% to 94% for mumps and 18% to 89% for rubella, 92% of the children tested seropositive for measles specific antibodies, 87% for mumps and 84% for rubella. The seroprevalence for measles, mumps and rubella was significantly higher for vaccinated than for unvaccinated children. Non-Swiss children had, without exception, a higher seroprevalence rate than Swiss children. Undergoing the disease did not influence the seroprevalence for measles, but it did so for mumps and rubella, for vaccinated and unvaccinated children alike. By analysis according to study site, we observed that sites with higher vaccination rates (e.g. Grabs in Rheintal) sometimes showed a lower seroprevalence than sites with lower vaccination rates (e.g. Langnau). This was the case for all three vaccines. This, together with other observations, shows that a booster is necessary for an adequate immunisation--as a wild virus infection or as a second vaccination.

Authors+Show Affiliations

Institut für Sozial- und Präventivmedizin, Universität Basel.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

10420798

Citation

Stohrer-Draxl, P, et al. "[Measles, Mumps and Rubella: Vaccination Rate and Seroprevalence in 8th Grade Students of 8 Different Sites in Switzerland 1995/96]." Praxis, vol. 88, no. 24, 1999, pp. 1069-77.
Stohrer-Draxl P, Amstad H, Grize L, et al. [Measles, mumps and rubella: vaccination rate and seroprevalence in 8th grade students of 8 different sites in Switzerland 1995/96]. Praxis (Bern 1994). 1999;88(24):1069-77.
Stohrer-Draxl, P., Amstad, H., Grize, L., Gassner, M., Takken-Sahli, K., Bourquin, C., & Braun-Fahrländer, C. (1999). [Measles, mumps and rubella: vaccination rate and seroprevalence in 8th grade students of 8 different sites in Switzerland 1995/96]. Praxis, 88(24), 1069-77.
Stohrer-Draxl P, et al. [Measles, Mumps and Rubella: Vaccination Rate and Seroprevalence in 8th Grade Students of 8 Different Sites in Switzerland 1995/96]. Praxis (Bern 1994). 1999 Jun 10;88(24):1069-77. PubMed PMID: 10420798.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Measles, mumps and rubella: vaccination rate and seroprevalence in 8th grade students of 8 different sites in Switzerland 1995/96]. AU - Stohrer-Draxl,P, AU - Amstad,H, AU - Grize,L, AU - Gassner,M, AU - Takken-Sahli,K, AU - Bourquin,C, AU - Braun-Fahrländer,C, PY - 1999/7/27/pubmed PY - 1999/7/27/medline PY - 1999/7/27/entrez SP - 1069 EP - 77 JF - Praxis JO - Praxis (Bern 1994) VL - 88 IS - 24 N2 - In 1987, the Swiss Federal Health Office (BAG) and the Swiss cantons launched the MMR-vaccination campaign. Within the frame of the SCARPOL Study, the vaccination status of 649, 8th class students was registered and serum samples were collected. The measles, mumps and rubella specific antibody levels were determined. The vaccination rate was 84% for measles, 74% for mumps, and 62% for rubella, 55% of these children had been vaccinated with the combined vaccine MMR. The vaccination rate for the different study areas varied from 70% to 95% for measles, 42% to 94% for mumps and 18% to 89% for rubella, 92% of the children tested seropositive for measles specific antibodies, 87% for mumps and 84% for rubella. The seroprevalence for measles, mumps and rubella was significantly higher for vaccinated than for unvaccinated children. Non-Swiss children had, without exception, a higher seroprevalence rate than Swiss children. Undergoing the disease did not influence the seroprevalence for measles, but it did so for mumps and rubella, for vaccinated and unvaccinated children alike. By analysis according to study site, we observed that sites with higher vaccination rates (e.g. Grabs in Rheintal) sometimes showed a lower seroprevalence than sites with lower vaccination rates (e.g. Langnau). This was the case for all three vaccines. This, together with other observations, shows that a booster is necessary for an adequate immunisation--as a wild virus infection or as a second vaccination. SN - 1661-8157 UR - https://www.unboundmedicine.com/medline/citation/10420798/[Measles_mumps_and_rubella:_vaccination_rate_and_seroprevalence_in_8th_grade_students_of_8_different_sites_in_Switzerland_1995/96]_ L2 - http://www.diseaseinfosearch.org/result/6369 DB - PRIME DP - Unbound Medicine ER -