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Extracting and visualizing matrix-assisted laser desorption/ionization time-of-flight mass spectral fingerprints.
Rapid Commun Mass Spectrom. 1999; 13(15):1586-94.RC

Abstract

We have developed a method for constructing and extracting matrix-assisted laser desorption/ionization (MALDI) fingerprints. This method is fully automated and statistically based, allowing a large number of spectra to be analyzed at a time in an objective manner. This method can be used to extract the fingerprint of a particular analyte from a spectrum containing multiple analytes. Therefore, this method lends itself well to real-world applications where samples to be analyzed are likely to be impure. We illustrate this method on experimental results from a series of studies of E. coli and B. atrophaeus MALDI time-of-flight mass spectrometry (TOFMS) fingerprints.

Authors+Show Affiliations

Jarman KH
Pacific Northwest National Laboratory, Richland, WA 99352, USA.
Daly DS
No affiliation info available
Petersen CE
No affiliation info available
Saenz AJ
No affiliation info available
Valentine NB
No affiliation info available
Wahl KL
No affiliation info available

MeSH

BacillusBacteriaEscherichia coliReproducibility of ResultsSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

10421901

Citation

Jarman, K H., et al. "Extracting and Visualizing Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectral Fingerprints." Rapid Communications in Mass Spectrometry : RCM, vol. 13, no. 15, 1999, pp. 1586-94.
Jarman KH, Daly DS, Petersen CE, et al. Extracting and visualizing matrix-assisted laser desorption/ionization time-of-flight mass spectral fingerprints. Rapid Commun Mass Spectrom. 1999;13(15):1586-94.
Jarman, K. H., Daly, D. S., Petersen, C. E., Saenz, A. J., Valentine, N. B., & Wahl, K. L. (1999). Extracting and visualizing matrix-assisted laser desorption/ionization time-of-flight mass spectral fingerprints. Rapid Communications in Mass Spectrometry : RCM, 13(15), 1586-94.
Jarman KH, et al. Extracting and Visualizing Matrix-assisted Laser Desorption/ionization Time-of-flight Mass Spectral Fingerprints. Rapid Commun Mass Spectrom. 1999;13(15):1586-94. PubMed PMID: 10421901.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extracting and visualizing matrix-assisted laser desorption/ionization time-of-flight mass spectral fingerprints. AU - Jarman,K H, AU - Daly,D S, AU - Petersen,C E, AU - Saenz,A J, AU - Valentine,N B, AU - Wahl,K L, PY - 1999/7/28/pubmed PY - 1999/7/28/medline PY - 1999/7/28/entrez SP - 1586 EP - 94 JF - Rapid communications in mass spectrometry : RCM JO - Rapid Commun Mass Spectrom VL - 13 IS - 15 N2 - We have developed a method for constructing and extracting matrix-assisted laser desorption/ionization (MALDI) fingerprints. This method is fully automated and statistically based, allowing a large number of spectra to be analyzed at a time in an objective manner. This method can be used to extract the fingerprint of a particular analyte from a spectrum containing multiple analytes. Therefore, this method lends itself well to real-world applications where samples to be analyzed are likely to be impure. We illustrate this method on experimental results from a series of studies of E. coli and B. atrophaeus MALDI time-of-flight mass spectrometry (TOFMS) fingerprints. SN - 0951-4198 UR - https://www.unboundmedicine.com/medline/citation/10421901/Extracting_and_visualizing_matrix_assisted_laser_desorption/ionization_time_of_flight_mass_spectral_fingerprints_ L2 - https://doi.org/10.1002/(SICI)1097-0231(19990815)13:15<1586::AID-RCM680>3.0.CO;2-2 DB - PRIME DP - Unbound Medicine ER -