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[Folate consumption in the preconception period of Sicilian pregnant women and their knowledge about the prevention of neural tube defect by folate supplementation].
Minerva Ginecol 1999; 51(5):177-81MG

Abstract

BACKGROUND AND AIMS

To define the frequency of Sicilian pregnant women taking folic acid during the periconceptional period (three months before and two months after conception) and how many are familiar with the preventive effects of folic acid on NTD.

METHODS

987 pregnant women from eastern Sicily, mainly with low incomes and low levels of education, most with secondary school certificates, underwent biochemical screening for Down's syndrome and NTD in the second trimester of pregnancy.

RESULTS

An anencephalous fetus was diagnosed (frequency 0.1%) in a non-risk couple who had not taken folic acid during the periconceptional period: 4.1% (41 cases) of pregnant women reported having taken folic acid before pregnancy and 12.3% (122) during the first two months of pregnancy: five (0.5%) took folic acid during the periconceptional period (three months before conception and two months after). None of the 5 patients with a positive family history of NTD had taken folic acid. In all 122 cases the intake of folic acid supplements during pregnancy started after the positive results of the pregnancy test or echographic evidence of pregnancy, namely between the fifth and eighth week of pregnancy. Only the 5 pregnant women (0.5%) who took folic acid during the periconceptional period were aware of the possibility of preventing NTD through supplements of this vitamin.

CONCLUSIONS

Greater efforts must be made to increase periconceptional use of folic acid for the prevention of NTD in pregnant women in Sicily.

Authors+Show Affiliations

Azienda Ospedali Vittorio Emanuele II, Ferrarotto Ospedale di Maternità S. Bambino, Catania.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ita

PubMed ID

10431526

Citation

Pepe, F, et al. "[Folate Consumption in the Preconception Period of Sicilian Pregnant Women and Their Knowledge About the Prevention of Neural Tube Defect By Folate Supplementation]." Minerva Ginecologica, vol. 51, no. 5, 1999, pp. 177-81.
Pepe F, Pepe P, Montaperto A, et al. [Folate consumption in the preconception period of Sicilian pregnant women and their knowledge about the prevention of neural tube defect by folate supplementation]. Minerva Ginecol. 1999;51(5):177-81.
Pepe, F., Pepe, P., Montaperto, A., Rotolo, N., Florio, M. L., & Uccellatore, F. (1999). [Folate consumption in the preconception period of Sicilian pregnant women and their knowledge about the prevention of neural tube defect by folate supplementation]. Minerva Ginecologica, 51(5), pp. 177-81.
Pepe F, et al. [Folate Consumption in the Preconception Period of Sicilian Pregnant Women and Their Knowledge About the Prevention of Neural Tube Defect By Folate Supplementation]. Minerva Ginecol. 1999;51(5):177-81. PubMed PMID: 10431526.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Folate consumption in the preconception period of Sicilian pregnant women and their knowledge about the prevention of neural tube defect by folate supplementation]. AU - Pepe,F, AU - Pepe,P, AU - Montaperto,A, AU - Rotolo,N, AU - Florio,M L, AU - Uccellatore,F, PY - 1999/8/4/pubmed PY - 1999/8/4/medline PY - 1999/8/4/entrez SP - 177 EP - 81 JF - Minerva ginecologica JO - Minerva Ginecol VL - 51 IS - 5 N2 - BACKGROUND AND AIMS: To define the frequency of Sicilian pregnant women taking folic acid during the periconceptional period (three months before and two months after conception) and how many are familiar with the preventive effects of folic acid on NTD. METHODS: 987 pregnant women from eastern Sicily, mainly with low incomes and low levels of education, most with secondary school certificates, underwent biochemical screening for Down's syndrome and NTD in the second trimester of pregnancy. RESULTS: An anencephalous fetus was diagnosed (frequency 0.1%) in a non-risk couple who had not taken folic acid during the periconceptional period: 4.1% (41 cases) of pregnant women reported having taken folic acid before pregnancy and 12.3% (122) during the first two months of pregnancy: five (0.5%) took folic acid during the periconceptional period (three months before conception and two months after). None of the 5 patients with a positive family history of NTD had taken folic acid. In all 122 cases the intake of folic acid supplements during pregnancy started after the positive results of the pregnancy test or echographic evidence of pregnancy, namely between the fifth and eighth week of pregnancy. Only the 5 pregnant women (0.5%) who took folic acid during the periconceptional period were aware of the possibility of preventing NTD through supplements of this vitamin. CONCLUSIONS: Greater efforts must be made to increase periconceptional use of folic acid for the prevention of NTD in pregnant women in Sicily. SN - 0026-4784 UR - https://www.unboundmedicine.com/medline/citation/10431526/[Folate_consumption_in_the_preconception_period_of_Sicilian_pregnant_women_and_their_knowledge_about_the_prevention_of_neural_tube_defect_by_folate_supplementation]_ L2 - https://medlineplus.gov/neuraltubedefects.html DB - PRIME DP - Unbound Medicine ER -