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The 1996 outbreak of dengue hemorrhagic fever in Delhi, India.

Abstract

A major outbreak of dengue hemorrhagic fever (DHF) affected more than 10,000 people in Delhi and neighboring areas in 1996. The outbreak started in September, peaked in October to November and lasted till early December. The clinical and laboratory data of 515 adult patients admitted to Lok Nayak Hospital, New Delhi were reviewed. Fever (100%), myalgias and malaise (96%), abdominal pain (10.2%) and vomiting (8.7%) were the prominent presenting features. Hemorrhagic manifestations were seen in all patients- a positive tourniquet test (21.2%), scattered petechial rash (23.07%), confluent rash (2.7%), epistaxis (38.4%), gum bleeds (28.06%) and hematemesis (22.86%) being the major bleeding manifestations. Hepatomegaly was observed in 96% of the patients. Laboratory investigations revealed thrombocytopenia, hemoconcentration and leukopenia. Serological confirmation with a microcapture ELISA technic was done in 143/515 patients. The mortality rate was 6.6% and, multiple bleeding manifestations, severe thrombocytopenia, hypoproteinemia and dengue shock syndrome (DSS) were associated with a higher mortality.

Authors+Show Affiliations

Department of Medicine, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10437946

Citation

Anuradha, S, et al. "The 1996 Outbreak of Dengue Hemorrhagic Fever in Delhi, India." The Southeast Asian Journal of Tropical Medicine and Public Health, vol. 29, no. 3, 1998, pp. 503-6.
Anuradha S, Singh NP, Rizvi SN, et al. The 1996 outbreak of dengue hemorrhagic fever in Delhi, India. Southeast Asian J Trop Med Public Health. 1998;29(3):503-6.
Anuradha, S., Singh, N. P., Rizvi, S. N., Agarwal, S. K., Gur, R., & Mathur, M. D. (1998). The 1996 outbreak of dengue hemorrhagic fever in Delhi, India. The Southeast Asian Journal of Tropical Medicine and Public Health, 29(3), 503-6.
Anuradha S, et al. The 1996 Outbreak of Dengue Hemorrhagic Fever in Delhi, India. Southeast Asian J Trop Med Public Health. 1998;29(3):503-6. PubMed PMID: 10437946.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The 1996 outbreak of dengue hemorrhagic fever in Delhi, India. AU - Anuradha,S, AU - Singh,N P, AU - Rizvi,S N, AU - Agarwal,S K, AU - Gur,R, AU - Mathur,M D, PY - 1999/8/7/pubmed PY - 1999/8/7/medline PY - 1999/8/7/entrez SP - 503 EP - 6 JF - The Southeast Asian journal of tropical medicine and public health JO - Southeast Asian J Trop Med Public Health VL - 29 IS - 3 N2 - A major outbreak of dengue hemorrhagic fever (DHF) affected more than 10,000 people in Delhi and neighboring areas in 1996. The outbreak started in September, peaked in October to November and lasted till early December. The clinical and laboratory data of 515 adult patients admitted to Lok Nayak Hospital, New Delhi were reviewed. Fever (100%), myalgias and malaise (96%), abdominal pain (10.2%) and vomiting (8.7%) were the prominent presenting features. Hemorrhagic manifestations were seen in all patients- a positive tourniquet test (21.2%), scattered petechial rash (23.07%), confluent rash (2.7%), epistaxis (38.4%), gum bleeds (28.06%) and hematemesis (22.86%) being the major bleeding manifestations. Hepatomegaly was observed in 96% of the patients. Laboratory investigations revealed thrombocytopenia, hemoconcentration and leukopenia. Serological confirmation with a microcapture ELISA technic was done in 143/515 patients. The mortality rate was 6.6% and, multiple bleeding manifestations, severe thrombocytopenia, hypoproteinemia and dengue shock syndrome (DSS) were associated with a higher mortality. SN - 0125-1562 UR - https://www.unboundmedicine.com/medline/citation/10437946/The_1996_outbreak_of_dengue_hemorrhagic_fever_in_Delhi_India_ DB - PRIME DP - Unbound Medicine ER -