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Necrotizing ulcerative periodontitis associated with severe congenital immunodeficiency in a prepubescent subject: clinical findings and response to intravenous immunoglobulin treatment.
J Clin Periodontol. 1999 Aug; 26(8):499-504.JC

Abstract

Common variable immunodeficiency (CVID) is a rare multifactorial congenital disease of genetic origin caused by an impairment in the secretion of specific immunoglobulins. It manifests systemically through recurrent respiratory infections, gastrointestinal disorders and autoimmune diseases. Oral manifestations may include gingivitis and lichenoid lesions with Wickham's striae. The treatment for CVID is supported by using intravenous infusion of immunoglobulins (IVIG) that allows for control of the disease and avoidance of recurrent opportunistic infections. This report presents a case of necrotizing ulcerative periodontitis (NUP) in a young patient with CVID, and correlates his periodontal status with systemic conditions before and after IVIG administration during 1 year of evaluation.

Authors+Show Affiliations

School of Dentistry of the Federal University of Rio de Janeiro, Brazil. erajr@zaz.com.brNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

10450809

Citation

Batista, E L., et al. "Necrotizing Ulcerative Periodontitis Associated With Severe Congenital Immunodeficiency in a Prepubescent Subject: Clinical Findings and Response to Intravenous Immunoglobulin Treatment." Journal of Clinical Periodontology, vol. 26, no. 8, 1999, pp. 499-504.
Batista EL, Novaes AB, Calvano LM, et al. Necrotizing ulcerative periodontitis associated with severe congenital immunodeficiency in a prepubescent subject: clinical findings and response to intravenous immunoglobulin treatment. J Clin Periodontol. 1999;26(8):499-504.
Batista, E. L., Novaes, A. B., Calvano, L. M., do Prado, E. A., Goudouris, E. S., & Batista, F. C. (1999). Necrotizing ulcerative periodontitis associated with severe congenital immunodeficiency in a prepubescent subject: clinical findings and response to intravenous immunoglobulin treatment. Journal of Clinical Periodontology, 26(8), 499-504.
Batista EL, et al. Necrotizing Ulcerative Periodontitis Associated With Severe Congenital Immunodeficiency in a Prepubescent Subject: Clinical Findings and Response to Intravenous Immunoglobulin Treatment. J Clin Periodontol. 1999;26(8):499-504. PubMed PMID: 10450809.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Necrotizing ulcerative periodontitis associated with severe congenital immunodeficiency in a prepubescent subject: clinical findings and response to intravenous immunoglobulin treatment. AU - Batista,E L,Jr AU - Novaes,A B,Jr AU - Calvano,L M, AU - do Prado,E A, AU - Goudouris,E S, AU - Batista,F C, PY - 1999/8/18/pubmed PY - 2001/3/28/medline PY - 1999/8/18/entrez SP - 499 EP - 504 JF - Journal of clinical periodontology JO - J Clin Periodontol VL - 26 IS - 8 N2 - Common variable immunodeficiency (CVID) is a rare multifactorial congenital disease of genetic origin caused by an impairment in the secretion of specific immunoglobulins. It manifests systemically through recurrent respiratory infections, gastrointestinal disorders and autoimmune diseases. Oral manifestations may include gingivitis and lichenoid lesions with Wickham's striae. The treatment for CVID is supported by using intravenous infusion of immunoglobulins (IVIG) that allows for control of the disease and avoidance of recurrent opportunistic infections. This report presents a case of necrotizing ulcerative periodontitis (NUP) in a young patient with CVID, and correlates his periodontal status with systemic conditions before and after IVIG administration during 1 year of evaluation. SN - 0303-6979 UR - https://www.unboundmedicine.com/medline/citation/10450809/Necrotizing_ulcerative_periodontitis_associated_with_severe_congenital_immunodeficiency_in_a_prepubescent_subject:_clinical_findings_and_response_to_intravenous_immunoglobulin_treatment_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0303-6979&date=1999&volume=26&issue=8&spage=499 DB - PRIME DP - Unbound Medicine ER -