Tags

Type your tag names separated by a space and hit enter

Epstein-Barr virus (EBV) infection and gastric carcinoma: the approach through EBV infected epithelial cell lines.
Jpn J Infect Dis 1999; 52(3):110-2JJ

Abstract

Epstein-Barr virus (EBV) infection is found in 7% of Japanese gastric carcinoma. Our strategy is to establish the EBV infected epithelial cell lines from EBV infected gastric carcinomas and to characterize the cell lines on the bases of cellular and molecular biology to define the etiological role of EBV. We have characterized two EBV positive cell lines, GT38 and GT39 from gastric tissues. The both cell lines were EBV latency type III and produced the virus spontaneously. The character of tumor cells was demonstrated by the colony formation in soft agar and the tumorigenesis in severe combined immunodeficient mice.

Authors+Show Affiliations

Department of Biosignaling, School of Life Science, Faculty of Medicine, Tottori University, Yonago, Japan. sairen@grape.med.tottori-u.ac.jp

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

10507989

Citation

Sairenji, T. "Epstein-Barr Virus (EBV) Infection and Gastric Carcinoma: the Approach Through EBV Infected Epithelial Cell Lines." Japanese Journal of Infectious Diseases, vol. 52, no. 3, 1999, pp. 110-2.
Sairenji T. Epstein-Barr virus (EBV) infection and gastric carcinoma: the approach through EBV infected epithelial cell lines. Jpn J Infect Dis. 1999;52(3):110-2.
Sairenji, T. (1999). Epstein-Barr virus (EBV) infection and gastric carcinoma: the approach through EBV infected epithelial cell lines. Japanese Journal of Infectious Diseases, 52(3), pp. 110-2.
Sairenji T. Epstein-Barr Virus (EBV) Infection and Gastric Carcinoma: the Approach Through EBV Infected Epithelial Cell Lines. Jpn J Infect Dis. 1999;52(3):110-2. PubMed PMID: 10507989.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epstein-Barr virus (EBV) infection and gastric carcinoma: the approach through EBV infected epithelial cell lines. A1 - Sairenji,T, PY - 1999/10/3/pubmed PY - 1999/10/3/medline PY - 1999/10/3/entrez SP - 110 EP - 2 JF - Japanese journal of infectious diseases JO - Jpn. J. Infect. Dis. VL - 52 IS - 3 N2 - Epstein-Barr virus (EBV) infection is found in 7% of Japanese gastric carcinoma. Our strategy is to establish the EBV infected epithelial cell lines from EBV infected gastric carcinomas and to characterize the cell lines on the bases of cellular and molecular biology to define the etiological role of EBV. We have characterized two EBV positive cell lines, GT38 and GT39 from gastric tissues. The both cell lines were EBV latency type III and produced the virus spontaneously. The character of tumor cells was demonstrated by the colony formation in soft agar and the tumorigenesis in severe combined immunodeficient mice. SN - 1344-6304 UR - https://www.unboundmedicine.com/medline/citation/10507989/Epstein_Barr_virus__EBV__infection_and_gastric_carcinoma:_the_approach_through_EBV_infected_epithelial_cell_lines_ L2 - https://medlineplus.gov/stomachcancer.html DB - PRIME DP - Unbound Medicine ER -