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Using gabapentin to treat neuropathic pain.
Can Fam Physician. 1999 Sep; 45:2109-12.CF

Abstract

OBJECTIVE

To review use of gabapentin as an adjuvant agent to treat neuropathic pain.

QUALITY OF EVIDENCE

MEDLINE was searched from 1995 to October 1998 for reports. There were approximately 20 citations. Additional articles from Pain and other medical journals were reviewed. No double-blind studies have examined gabapentin and its use as an analgesic adjuvant agent.

MAIN MESSAGE

Gabapentin is an anticonvulsant medication used recently as an effective adjuvant agent for treating neuropathic pain. It is a structural analogue of gamma-aminobutyric acid (GABA), but its receptor and biochemical function remain unknown. Gabapentin has desirable pharmacokinetic properties and acceptable side effects, which simplify its use. There are very few interactions between gabapentin and other medications, and gabapentin is well tolerated.

CONCLUSION

Gabapentin could be an effective adjuvant agent for many neuropathic pain states.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

10509223

Citation

Hays, H, and M A. Woodroffe. "Using Gabapentin to Treat Neuropathic Pain." Canadian Family Physician Medecin De Famille Canadien, vol. 45, 1999, pp. 2109-12.
Hays H, Woodroffe MA. Using gabapentin to treat neuropathic pain. Can Fam Physician. 1999;45:2109-12.
Hays, H., & Woodroffe, M. A. (1999). Using gabapentin to treat neuropathic pain. Canadian Family Physician Medecin De Famille Canadien, 45, 2109-12.
Hays H, Woodroffe MA. Using Gabapentin to Treat Neuropathic Pain. Can Fam Physician. 1999;45:2109-12. PubMed PMID: 10509223.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Using gabapentin to treat neuropathic pain. AU - Hays,H, AU - Woodroffe,M A, PY - 1999/10/6/pubmed PY - 1999/10/6/medline PY - 1999/10/6/entrez SP - 2109 EP - 12 JF - Canadian family physician Medecin de famille canadien JO - Can Fam Physician VL - 45 N2 - OBJECTIVE: To review use of gabapentin as an adjuvant agent to treat neuropathic pain. QUALITY OF EVIDENCE: MEDLINE was searched from 1995 to October 1998 for reports. There were approximately 20 citations. Additional articles from Pain and other medical journals were reviewed. No double-blind studies have examined gabapentin and its use as an analgesic adjuvant agent. MAIN MESSAGE: Gabapentin is an anticonvulsant medication used recently as an effective adjuvant agent for treating neuropathic pain. It is a structural analogue of gamma-aminobutyric acid (GABA), but its receptor and biochemical function remain unknown. Gabapentin has desirable pharmacokinetic properties and acceptable side effects, which simplify its use. There are very few interactions between gabapentin and other medications, and gabapentin is well tolerated. CONCLUSION: Gabapentin could be an effective adjuvant agent for many neuropathic pain states. SN - 0008-350X UR - https://www.unboundmedicine.com/medline/citation/10509223/Using_gabapentin_to_treat_neuropathic_pain_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/10509223/ DB - PRIME DP - Unbound Medicine ER -