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Thyroid autoimmunity in children and adolescents with Type 1 diabetes mellitus.
Diabetes Nutr Metab. 1999 Feb; 12(1):27-31.DN

Abstract

Type 1 diabetic children and adolescents often present with autoimmune thyroid disorders. Two hundred and four diabetic patients, less than 20 years old, were studied in order to diagnose these diseases. The prevalence of thyroid autoimmune disorders was 17.6% and, of those, chronic autoimmune thyroiditis was the most frequent. Microsomal autoantibodies correlated more accurately with the presence of chronic autoimmune thyroiditis than thyroglobulin autoantibodies. The thyroid status of most of the patients with positive markers was euthyroidism (77%), but subclinical hypothyroidism (11%), overt hypothyroidism (3%), subclinical hyperthyroidism (3%) and overt hyperthyroidism (6%) were also present. Autoimmune thyroid disorders were the most prevalent immunological processes affecting diabetic patients. No significant associations of thyroid autoimmunity and other autoimmunological disorders, such as celiac disease or presence of other autoimmune antibodies, were found.

Authors+Show Affiliations

Department of Pediatrics, Ramón y Cajal Hospital, Alcalá de Henares University School of Medicine, Madrid, Spain.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10517303

Citation

Roldán, M B., et al. "Thyroid Autoimmunity in Children and Adolescents With Type 1 Diabetes Mellitus." Diabetes, Nutrition & Metabolism, vol. 12, no. 1, 1999, pp. 27-31.
Roldán MB, Alonso M, Barrio R. Thyroid autoimmunity in children and adolescents with Type 1 diabetes mellitus. Diabetes Nutr Metab. 1999;12(1):27-31.
Roldán, M. B., Alonso, M., & Barrio, R. (1999). Thyroid autoimmunity in children and adolescents with Type 1 diabetes mellitus. Diabetes, Nutrition & Metabolism, 12(1), 27-31.
Roldán MB, Alonso M, Barrio R. Thyroid Autoimmunity in Children and Adolescents With Type 1 Diabetes Mellitus. Diabetes Nutr Metab. 1999;12(1):27-31. PubMed PMID: 10517303.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Thyroid autoimmunity in children and adolescents with Type 1 diabetes mellitus. AU - Roldán,M B, AU - Alonso,M, AU - Barrio,R, PY - 1999/10/12/pubmed PY - 1999/10/12/medline PY - 1999/10/12/entrez SP - 27 EP - 31 JF - Diabetes, nutrition & metabolism JO - Diabetes Nutr. Metab. VL - 12 IS - 1 N2 - Type 1 diabetic children and adolescents often present with autoimmune thyroid disorders. Two hundred and four diabetic patients, less than 20 years old, were studied in order to diagnose these diseases. The prevalence of thyroid autoimmune disorders was 17.6% and, of those, chronic autoimmune thyroiditis was the most frequent. Microsomal autoantibodies correlated more accurately with the presence of chronic autoimmune thyroiditis than thyroglobulin autoantibodies. The thyroid status of most of the patients with positive markers was euthyroidism (77%), but subclinical hypothyroidism (11%), overt hypothyroidism (3%), subclinical hyperthyroidism (3%) and overt hyperthyroidism (6%) were also present. Autoimmune thyroid disorders were the most prevalent immunological processes affecting diabetic patients. No significant associations of thyroid autoimmunity and other autoimmunological disorders, such as celiac disease or presence of other autoimmune antibodies, were found. SN - 0394-3402 UR - https://www.unboundmedicine.com/medline/citation/10517303/Thyroid_autoimmunity_in_children_and_adolescents_with_Type_1_diabetes_mellitus_ L2 - http://www.diseaseinfosearch.org/result/8214 DB - PRIME DP - Unbound Medicine ER -