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Drug treatment of common STDs: part I. Herpes, syphilis, urethritis, chlamydia and gonorrhea.
Am Fam Physician. 1999 Oct 01; 60(5):1387-94.AF

Abstract

In 1998, the Centers for Disease Control and Prevention released guidelines for the treatment of sexually transmitted diseases. Several treatment advances have been made since the previous guidelines were published. Part I of this two-part article describes current recommendations for the treatment of genital ulcer diseases, urethritis and cervicitis. Treatment advances include effective single-dose regimens for many sexually transmitted diseases and improved therapies for herpes infections. Two single-dose regimens, 1 g of oral azithromycin and 250 mg of intramuscular ceftriaxone, are effective for the treatment of chancroid. A three-day course of 500 mg of oral ciprofloxacin twice daily may be used to treat chancroid in patients who are not pregnant. Parenteral penicillin continues to be the drug of choice for treatment of all stages of syphilis. Three antiviral medications have been shown to provide clinical benefit in the treatment of genital herpes: acyclovir, valacyclovir and famciclovir. Valacyclovir and famciclovir are not yet recommended for use during pregnancy. Azithromycin in a single oral 1-g dose is now a recommended regimen for the treatment of nongonococcal urethritis.

Authors+Show Affiliations

West Virginia University Hospitals, Morgantown 26506-8045, USA.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

10524484

Citation

Woodward, C, and M A. Fisher. "Drug Treatment of Common STDs: Part I. Herpes, Syphilis, Urethritis, Chlamydia and Gonorrhea." American Family Physician, vol. 60, no. 5, 1999, pp. 1387-94.
Woodward C, Fisher MA. Drug treatment of common STDs: part I. Herpes, syphilis, urethritis, chlamydia and gonorrhea. Am Fam Physician. 1999;60(5):1387-94.
Woodward, C., & Fisher, M. A. (1999). Drug treatment of common STDs: part I. Herpes, syphilis, urethritis, chlamydia and gonorrhea. American Family Physician, 60(5), 1387-94.
Woodward C, Fisher MA. Drug Treatment of Common STDs: Part I. Herpes, Syphilis, Urethritis, Chlamydia and Gonorrhea. Am Fam Physician. 1999 Oct 1;60(5):1387-94. PubMed PMID: 10524484.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Drug treatment of common STDs: part I. Herpes, syphilis, urethritis, chlamydia and gonorrhea. AU - Woodward,C, AU - Fisher,M A, PY - 1999/10/19/pubmed PY - 1999/10/19/medline PY - 1999/10/19/entrez SP - 1387 EP - 94 JF - American family physician JO - Am Fam Physician VL - 60 IS - 5 N2 - In 1998, the Centers for Disease Control and Prevention released guidelines for the treatment of sexually transmitted diseases. Several treatment advances have been made since the previous guidelines were published. Part I of this two-part article describes current recommendations for the treatment of genital ulcer diseases, urethritis and cervicitis. Treatment advances include effective single-dose regimens for many sexually transmitted diseases and improved therapies for herpes infections. Two single-dose regimens, 1 g of oral azithromycin and 250 mg of intramuscular ceftriaxone, are effective for the treatment of chancroid. A three-day course of 500 mg of oral ciprofloxacin twice daily may be used to treat chancroid in patients who are not pregnant. Parenteral penicillin continues to be the drug of choice for treatment of all stages of syphilis. Three antiviral medications have been shown to provide clinical benefit in the treatment of genital herpes: acyclovir, valacyclovir and famciclovir. Valacyclovir and famciclovir are not yet recommended for use during pregnancy. Azithromycin in a single oral 1-g dose is now a recommended regimen for the treatment of nongonococcal urethritis. SN - 0002-838X UR - https://www.unboundmedicine.com/medline/citation/10524484/Drug_treatment_of_common_STDs:_part_I__Herpes_syphilis_urethritis_chlamydia_and_gonorrhea_ L2 - https://www.aafp.org/link_out?pmid=10524484 DB - PRIME DP - Unbound Medicine ER -